1164200

达非那新氢溴酸盐 氢溴酸盐

United States Pharmacopeia (USP) Reference Standard

• 别名: UK 88525–04, （3S）-1- [2-（2,3-二氢-5-苯并呋喃基）乙基]-α,α-二苯基-3-吡咯烷乙酰胺 氢溴酸盐
• 经验公式（希尔记法）: C₂₈H₃₀N₂O₂ · HBr
• CAS号: 133099-07-7
• 分子量: 507.46
• MDL號碼: MFCD08141803
• 分類程式碼代碼: 41116107
• NACRES: NA.24

属性

• API 家族: darifenacin
• 形狀: solid
• 製造商／商標名: USP
• 應用: pharmaceutical
• SMILES 字串: O=C(N)C([C@H]1CN(CCC2=CC=C(OCC3)C3=C2)CC1)(C4=CC=CC=C4)C5=CC=CC=C5.Br
• InChI: 1S/C28H30N2O2.BrH/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26;/h1-12,19,25H,13-18,20H2,(H2,29,31);1H/t25-;/m1./s1
• InChI 密鑰: UQAVIASOPREUIT-VQIWEWKSSA-N
• 基因資訊: human ... CHRM2(1129) , CHRM3(1131)

说明

一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

應用

Darifenacin hydrobromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

生化／生理作用

氢溴酸达非那新是一种解痉挛毒蕈碱拮抗剂，对阻断M3毒蕈碱乙酰胆碱受体具有选择性，M3毒蕈碱乙酰胆碱受体主要负责膀胱肌肉的收缩。 氢溴酸达非那新对M3的亲和力分别比M1和M5高9和12倍，对M3的亲和力比M2和M4分别高59倍。 达非那新在临床上可用于治疗尿失禁和膀胱过度活动症。

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable