PHL89593

(S)-(+)-喜树碱

phyproof^® Reference Substance

• 别名: (S)-(+)-Camptothecin
• 经验公式（希尔记法）: C₂₀H₁₆N₂O₄
• CAS号: 7689-03-4
• 分子量: 348.35
• Beilstein: 631069
• MDL编号: MFCD00081076
• UNSPSC代码: 41116107
• NACRES: NA.24

属性

• 等级: primary reference standard
• 产品线: phyproof^® Reference Substance
• 方案: ≥90.0% (HPLC)
• 表单: powder
• 制造商/商品名称: PhytoLab
• mp: 260 °C (dec.) (lit.)
• 储存温度: 2-8°C
• SMILES字符串: CC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5ccccc5nc34)C2=O
• InChI: 1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1
• InChI key: VSJKWCGYPAHWDS-FQEVSTJZSA-N

说明

一般描述

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

应用

• Co-delivery system for camptothecin and doxorubicin: Research on dendritic polymer prodrug-based unimolecular micelles demonstrated a pH-responsive co-delivery mechanism for camptothecin and doxorubicin, offering a synergistic effect in controlled drug release (Chen and Liu, 2024).



• Investigation into camptothecin′s role in chronic myeloid leukemia: The study explored the therapeutic potential of FL118, a camptothecin derivative, against chronic myeloid leukemia resistant to BCR-ABL inhibitors, targeting RNA helicase DDX5 (Takeda et al., 2024).

法律信息

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

安全信息

• 象形图: GHS06,GHS08
• 警示用语：: Danger
• 危险声明: H301,H340
• 预防措施声明: P202 - P264 - P270 - P280 - P301 + P310 - P405
• 危险分类: Acute Tox. 3 Oral - Muta. 1B
• 储存分类代码: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable