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V6383

Sigma-Aldrich

长春西汀

≥98%, solid

别名:

(3α,16α)-Eburnamenine-14-carboxylic acid ethyl ester, Eburnamenine-14-carboxylic acid ethyl ester

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About This Item

经验公式（希尔记法）:
C22H26N2O2
CAS号:
42971-09-5
分子量:
350.45
EC 号:
256-028-0
MDL编号:
MFCD00211233
UNSPSC代码:
41106305
PubChem化学物质编号:
24278182
NACRES:
NA.77

质量水平

200

方案

≥98%

表单

solid

颜色

white

溶解性

DMSO: 5 mg/mL
H2O: insoluble

SMILES字符串

[H][C@]12N3CCC[C@@]1(CC)C=C(C(=O)OCC)n4c2c(CC3)c5ccccc45

InChI

1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1

InChI key

DDNCQMVWWZOMLN-IRLDBZIGSA-N

基因信息

human ... PDE1A(5136) , PDE1B(5153) , PDE1C(5137)

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生化/生理作用

Ca2+-calmodulin-dependent phosphodiesterase I (PDE1) inhibitor.

特点和优势

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

注意

Photosensitive

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险声明

H302

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
056H0188
128H0788
099H0884
099H0883
010K1165

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Balazs Gulyas et al.
Current radiopharmaceuticals, 5(1), 19-28 (2011-11-15)
With the main objective of comparing the prospective diagnostic power of two 11C-labelled molecular imaging biomarkers with affinity for TSPO and used for the visualisation of activated microglia after a stroke, we measured with positron emission tomography (PET) in four
Crystal L Lantz et al.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 30(5), 351-357 (2012-05-24)
There is growing evidence that deficits in neuronal plasticity underlie the cognitive problems seen in fetal alcohol spectrum disorders (FASD). However, the mechanisms behind these deficits are not clear. Here we test the effects of early alcohol exposure on ocular
Yan-Ting Mao et al.
Die Pharmazie, 68(5), 381-382 (2013-06-28)
The purpose of the present study was to develop a novel transdermal vinpocetine patch containing a stable formulation and with good entrapment efficiency, and percutaneous absorption which via ethosome. Ethosome was found to be a more efficient delivery carrier with
Balázs Gulyás et al.
Journal of the neurological sciences, 320(1-2), 110-117 (2012-07-31)
Although there is increasing evidence for microglial activation after an ischaemic stroke in the infarct core and the peri-infarct region, the "evolution" of the process in stroke patients is poorly known. Using PET and [((11))C]vinpocetine, we measured the regional changes
Sazal Patyar et al.
Pharmacological reports : PR, 63(3), 618-628 (2011-08-23)
A cerebrovascular accident, or stroke, is defined as the abrupt onset of a neurological deficit, which can be due to ischemia. Cerebral ischemia is caused by a reduction in blood flow that thereby decreases cerebral metabolism. Chronic cerebral hypoperfusion leads
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