所有图片(1)
About This Item
经验公式（希尔记法）:
C10H10N2O2S
CAS号:
分子量:
222.26
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
价格与库存信息目前不能提供
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方案
≥98% (HPLC)
表单
needles
储存条件
protect from light
颜色
white
mp
63-64.4 °C
溶解性
DMSO: >10 mg/mL
储存温度
2-8°C
SMILES字符串
CN1SC(=O)N(Cc2ccccc2)C1=O
InChI
1S/C10H10N2O2S/c1-11-9(13)12(10(14)15-11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3
InChI key
JDSJDASOXWCHPN-UHFFFAOYSA-N
生化/生理作用
TDZD-8是GSK-3的一种选择性抑制剂、一种酰二唑烷酮衍生物、GSK-3β的一种非ATP竞争性抑制剂（IC50 = 2 μM）。它在>100 μM时不会抑制Cdk-1/cyclin B、CK-II、PKA或PKC。TDZD-8已被提出会与GSK-3β的激酶位点结合。
TDZD-8是GSK-3的一种选择性抑制剂。
制备说明
TDZD-8以大于10 mg/ml的浓度溶于DMSO。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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