所有图片(1)
About This Item
经验公式（希尔记法）:
C29H36N6O6S
CAS号:
分子量:
596.70
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.32
推荐产品
品質等級
化驗
≥95% (HPLC)
形狀
powder
分子量
59670 g/mol
技術
toxicology assay: suitable
溶解度
DMF: 20 mg/mL, clear, colorless to yellow
適合性
suitable for molecular biology
儲存溫度
−20°C
SMILES 字串
CSCC[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc3ccccc3)C(N)=O
InChI
1S/C29H36N6O6S/c1-42-12-11-22(33-27(39)20(30)14-18-16-32-21-10-6-5-9-19(18)21)28(40)35-24(15-25(36)37)29(41)34-23(26(31)38)13-17-7-3-2-4-8-17/h2-10,16,20,22-24,32H,11-15,30H2,1H3,(H2,31,38)(H,33,39)(H,34,41)(H,35,40)(H,36,37)/t20-,22-,23-,24-/m0/s1
InChI 密鑰
RGYLYUZOGHTBRF-BIHRQFPBSA-N
基因資訊
human ... CCK(885)
rat ... Cckbr(25706)
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Amino Acid Sequence
Trp-Met-Asp-Phe-NH2
一般說明
Research area: Neuroscience
Several biologically active fragments of the neuropeptide cholecystokinin (CCK) are present in the brain, where they interact with CCK-A and CCK-B receptors. Among these fragments, CCK-4 is notably abundant in the cortical and limbic brain structures. CCK-4, a bioactive form of cholecystokinin, is a peptide hormone that regulates food intake by binding to CCK receptors in the gut and brain.
Several biologically active fragments of the neuropeptide cholecystokinin (CCK) are present in the brain, where they interact with CCK-A and CCK-B receptors. Among these fragments, CCK-4 is notably abundant in the cortical and limbic brain structures. CCK-4, a bioactive form of cholecystokinin, is a peptide hormone that regulates food intake by binding to CCK receptors in the gut and brain.
應用
胆囊收缩素片段 30-33 酰胺可用于灭活 CCK8 抗血清。 该产品还可作为抗原，用于检测抗血清的特异性吸收控制。
生化／生理作用
胆囊收缩素片段 30-33 酰胺也称为 CCK-4 或 Trp-Met-Asp-Phe 酰胺是衍生自肽激素胆囊收缩素的肽片段。CCK-4 是引起人惊恐发作的惊恐试剂。该化合物的这一特性可用在科学研究中测试新的抗焦虑药。
包裝
无底玻璃瓶。内含物装在插入的融合锥内。
準備報告
胆囊收缩素片段 30-33 酰胺溶于二甲基甲酰胺中，浓度为 20 mg/ml，得到澄清、无色至黄色的溶液。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Andreas Ströhle et al.
Journal of psychiatric research, 43(12), 1013-1017 (2009-03-18)
Regular physical activity is anxiolytic in both healthy subjects and patients with panic disorder. In contrast, acute exercise may induce acute panic attacks or increase subjective anxiety in patients with panic disorder more than in other people. The effects of
Thérèse Schunck et al.
Journal of psychopharmacology (Oxford, England), 25(1), 52-59 (2010-05-26)
Benzodiazepine effects on cholecystokinin tetrapeptide (CCK-4)-induced panic attack (PA) in humans are incompletely characterized, in particular on the neurofunctional level. This work explores the effects of lorazepam on brain activity and behavioral and physiological symptoms related to CCK-4-induced PA in
Innar Tõru et al.
Psychiatry research, 178(2), 342-347 (2010-05-18)
In this study we examined how personality disposition may affect the response to cholecystokinin tetrapeptide (CCK-4; 50 microg) challenge in healthy volunteers (n=105). Personality traits were assessed with the Swedish universities Scales of Personality (SSP). Statistical methods employed were correlation
Rainer Rupprecht et al.
Science (New York, N.Y.), 325(5939), 490-493 (2009-06-23)
Most antianxiety drugs (anxiolytics) work by modulating neurotransmitters in the brain. Benzodiazepines are fast and effective anxiolytic drugs; however, their long-term use is limited by the development of tolerance and withdrawal symptoms. Ligands of the translocator protein [18 kilodaltons (kD)]
Cannabinoid receptors and cholecystokinin in feeding inhibition
Francisco A, et al.
Vitamins and Hormones (2013)
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