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Merck

SML3990

Sigma-Aldrich

BODIPY FL-NHS ester

new

≥98% (HPLC)

别名:

(T-4)-[1-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN]-1-oxopropoxy]-2,5-pyrrolidinedionato]difluoroboron, BDP FL NHS ester, BDP FL SE, BODIPY FL NHS, Bodipy FL succinimidyl ester

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About This Item

经验公式(希尔记法):
C18H18BF2N3O4
分子量:
389.16
分類程式碼代碼:
12352107
分類程式碼代碼:
12352200

品質等級

化驗

≥98% (HPLC)

形狀

powder

顏色

, Light orange to very dark red

溶解度

DMSO: 2 mg/mL, clear

儲存溫度

-10 to -25°C

SMILES 字串

O=C(CCC1=CC=C2C=C3C(C)=CC(C)=[N]3[B+3]([F-])([N-]21)[F-])ON4C(CCC4=O)=O

生化/生理作用

Amine reactive green fluorescent dye that can be used to label molecules like antibodies, proteins, peptides, and nucleic acids.



BODIPY FL-NHS ester is a versatile amine sensitive fluorescent labeling reagent that can be used to tag antibodies, proteins, peptides, and nucleic acids. BODIPY (boron-dipyrromethene) dyes are known for their excellent photophysical properties, including high fluorescence quantum yield, good photostability, and wide spectral tunability. BODIPY FL has a distinctive absorption peak (excitation) at 503-505 nm and an emission peak at 512-514 nm, resulting in bright green fluorescence. BODIPY FL is used in a wide range of applications, including immunofluorescence, live cell imaging, FRET experiments, and other fluorescence-based studies.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Shengrong Pei et al.
Bioconjugate chemistry, 34(12), 2194-2204 (2023-09-25)
α6β4* nicotinic acetylcholine receptor (nAChR) (* represents the possible presence of additional subunits) is mainly distributed in the central and peripheral nervous system and is associated with neurological diseases, such as neuropathic pain; however, the ability to explore its function
Jenna M Franke et al.
Journal of the American Chemical Society, 141(32), 12824-12831 (2019-07-25)
Fluorophores based on the BODIPY scaffold are prized for their tunable excitation and emission profiles, mild syntheses, and biological compatibility. Improving the water-solubility of BODIPY dyes remains an outstanding challenge. The development of water-soluble BODIPY dyes usually involves direct modification
Jun Yang et al.
The Journal of pharmacology and experimental therapeutics, 321(2), 462-468 (2007-02-10)
Despite the widely accepted assumption that most endosomal compartments are acidic, evaluation of the efficiency of pH-dependent drug release from a ligand-targeted drug conjugate during receptor-mediated endocytosis is lacking. Therefore, we have characterized the kinetics of pH-dependent drug release from

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