SML0445

克立马丁 富马酸盐

≥98% (HPLC)

• 别名: (+)-2-[2-[(p-Chloro-α-methyl-α-phenylbenzyl)oxy]ethyl]-1-methylpyrrolidine fumarate salt, (2R)-2-[2-[(1R)-1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine fumarate salt, 1-Methyl-2-[2-(α-methyl-p-chlorobenzhydryloxy)ethyl]pyrrolidine fumarate salt, 1-Methyl-2-[2-(methyl-p-chlorodiphenylmethyloxy)ethyl]pyrrolidine fumarate salt, Meclastine fumarate salt, Mecloprodine
• 经验公式（希尔记法）: C₂₁H₂₆ClNO · C₄H₄O₄
• CAS号: 14976-57-9
• 分子量: 459.96
• EC號碼: 239-055-2
• MDL號碼: MFCD00137486
• 分類程式碼代碼: 12352200
• PubChem物質ID: 329824727
• NACRES: NA.77

属性

• 品質等級: 100
• 化驗: ≥98% (HPLC)
• 形狀: powder
• 光學活性: [α]/D +15 to +25°, c = 1 in methanol
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: DMSO: 5 mg/mL (clear solution; warmed)
• 儲存溫度: room temp
• SMILES 字串: OC(=O)\C=C\C(O)=O.CN1CCC[C@@H]1CCO[C@](C)(c2ccccc2)c3ccc(Cl)cc3
• InChI: 1S/C21H26ClNO.C4H4O4/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2;5-3(6)1-2-4(7)8/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+/t20-,21-;/m1./s1
• InChI 密鑰: PMGQWSIVQFOFOQ-YKVZVUFRSA-N
• 基因資訊: human ... HRH1(3269)

说明

一般說明

Clemastine fumarate is used to treat multiple sclerosis, sneezing and rhinorrhea linked to common cold. It stimulates oligodendrocyte progenitor cell (OPC) differentiation and myelination.

應用

Clemastine fumarate salt has been used as a stimulator of rodent oligodendrocyte generation and myelination in vitro and in vivo.

生化／生理作用

Clemastine fumarate is an antihistamine H1-antagonist and anticholinergic that also has antipruritic activity.

Clemastine fumarate is an antihistamine H1-antagonist and anticholinergic.

特點和優勢

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable