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SHCLNG

Sigma-Aldrich

MISSION® shRNA

Bacterial Stock

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About This Item

UNSPSC代码:
41106609
To order shRNA please search for your gene of interest.
Order By Gene

质量水平

200

运输

dry ice

储存温度

−70°C

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一般描述

我们全面的shRNA产品系列包括超过150,000个预克隆的shRNA构建体，靶向超过15,000个人类基因和15,000个小鼠基因。该文库可用于：基因家族集合：与特定功能类（如激酶和离子通道）相关的基因集合；基因靶标集合，针对靶标基因的shRNA克隆集合；以及单个shRNA克隆。我们的shRNA和慢病毒制造平台利用专门实验室，配备最先进的机器人技术、液体处理和实验室信息管理系统（LIMS），为您的RNAi研究需求提供卓越的质量和服务。
MISSION® TRC shRNA bacterial glycerol stocks offer a renewable resource for shRNA plasmids. These plasmids can then be transfected directly, or packaged into lentiviral particles.

应用

MISSION® shRNA has been used in the generation of damage-regulated autophagy modulator (DRAM) and p73 knockdown cell lines.[1] It has also been used in lentivirus generation and gene knockdown[2] and to investigate the contribution of PAX8 (paired box 8) in ovarian cancer progression.[3]

其他说明

想要查看实验方案和应用数据，请访问 sigma.com/shrna。

法律信息

使用本产品需遵守一个或多个 许可协议。
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

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Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells
Humbert M, et al.
Leukemia Research, 36(12), 1552-1556 (2012)
A role for PAX8 in the tumorigenic phenotype of ovarian cancer cells
Di P, et al.
BMC Cancer, 14(1), 292-292 (2014)
Evidence of an oncogenic role of aberrant TOX activation in cutaneous T-cell lymphoma
Huang Y, et al.
Blood, 125(9), 1435-1443 (2015)
Nicola Currey et al.
Cellular and molecular gastroenterology and hepatology, 7(4), 819-839 (2019-03-05)
The early events by which inflammation promotes cancer are still not fully defined. The MCC gene is silenced by promoter methylation in colitis-associated and sporadic colon tumors, but its functional significance in precancerous lesions or polyps is not known. Here
Sun-Ji Park et al.
Free radical biology & medicine, 108, 44-55 (2017-03-23)
Luteal regression is a natural and necessary event to regulate the reproductive process in all mammals. Prostaglandin F2α (PGF2α) is the main factor that causes functional and structural regression of the corpus luteum (CL). It is well known that PGF2α-mediated
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商品

MISSION® Lentiviral shRNA

MISSION shRNA reduce the expression of specific target genes by targeting the specific mRNA therefore reducing the corresponding protein expression.

MISSION® Lentiviral shRNA

MISSION shRNA reduce the expression of specific target genes by targeting the specific mRNA therefore reducing the corresponding protein expression.

MISSION® Lentiviral shRNA

MISSION shRNA reduce the expression of specific target genes by targeting the specific mRNA therefore reducing the corresponding protein expression.

MISSION® Lentiviral shRNA

MISSION shRNA reduce the expression of specific target genes by targeting the specific mRNA therefore reducing the corresponding protein expression.

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相关内容

shRNAs for Individual Genes

Find shRNAs for Individual Genes. Over 150,000 pre-cloned shRNA constructs targeting more than 15,000 human and 15,000 mouse genes.

单独基因的shRNA

寻找单独基因的shRNA超过150,000个预克隆的shRNA构建体，靶向超过15,000个人类基因和15,000个小鼠基因。

Questions

  1. Do you provide a non-targeting shRNA standard in bacterial glycerol stock format?

    1 answer

    1. We solely offer the controls as plasmid DNA or lentiviral particles. If there is a need to create a glycerol stock, we typically utilize DH5alpha for this purpose.

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