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生物源
mouse
品質等級
共軛
unconjugated
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
4E7, monoclonal
分子量
67 kDa
物種活性
mouse, monkey, human, rat
技術
direct ELISA: 1:10,000
flow cytometry: 1:200-1:400
immunohistochemistry: 1:200-1:1,000
indirect immunofluorescence: 1:200-1:1,000
western blot: 1:500-1:2,000
同型
IgG2b
NCBI登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... AIF(9131)
相关类别
一般說明
AIFM1 (apoptosis inducing factor mitochondria associated 1) codes for apoptosis-inducing factor 1(AIF). It is located on human chromosome Xq26.1. AIF is a caspase-independent cell death effector.
免疫原
Purified recombinant fragment of human AIF expressed in E.coli.
Mouse monoclonal antibody raised against AIF
Mouse monoclonal antibody raised against AIF
生化／生理作用
AIFM1 (apoptosis inducing factor mitochondria associated 1) possesses redox activity, which helps in oxidative phosphorylation. In the mitochondria, AIFM1 helps in assembling or maintaining the mitochondrial respiratory complexes I and III. It plays a vital role in apoptosis. This gene is associated with COXPD6 (combined oxidative phosphorylation deficiency, encephalomyopathy, Cowchock syndrome and X-linked deafness with neuropathy.
外觀
Ascitic fluid containing 0.03% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Spondyloepimetaphyseal dysplasia with neurodegeneration associated with AIFM1 mutation?a novel phenotype of the mitochondrial disease.
Mierzewska H, et al.
Clinical Genetics, 91(1), 30-37 (2017)
Influenza virus infection induces translocation of apoptosis-inducing factor (AIF) in A549 cells: role of AIF in apoptosis and viral propagation.
Qu X, et al.
Archives of Virology, 162(3), 669-675 (2017)
A newly distal hereditary motor neuropathy caused by a rare AIFM1 mutation.
Sancho P, et al.
Neurogenetics, 18(4), 245-250 (2017)
X-linked hypomyelination with spondylometaphyseal dysplasia (H-SMD) associated with mutations in AIFM1.
Noriko M, et al.
Neurogenetics, 18(4), 185?194-185?194 (2017)
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