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Merck
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文件

S7635

Sigma-Aldrich

磺酰罗丹明 101

Dye content ~95 %, Powder

别名:

SR101; 2-(3-氧杂-23-氮杂-9-氮阳离子庚环[17.7.1.15,9.02,17.04,15.023,27.013,28]二十八烷-1(27),2(17),4,9(28),13,15,18-庚烷-16-基)-5-磺基苯磺酸盐

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About This Item

经验公式（希尔记法）:
C31H30N2O7S2
CAS号:
60311-02-6
分子量:
606.71
Beilstein:
3582548
EC號碼:
262-159-4
MDL號碼:
MFCD00012407
分類程式碼代碼:
12171500
PubChem物質ID:
24899749
NACRES:
NA.47

product name

磺酰罗丹明 101, Dye content ~95 %

形狀

powder

成份

Dye content, ~95%

顏色

black
dark green to brown

溶解度

methanol: 1 mg/mL

&epsilon ；(消光係數)

≥105000 at 573-579 nm in ethanol

螢光

λex 586 nm; λem 605 nm in H2O

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

room temp

SMILES 字串

OS(=O)(=O)c1ccc(C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)c(c1)S([O-])(=O)=O

InChI

1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)

InChI 密鑰

COIVODZMVVUETJ-UHFFFAOYSA-N

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相关类别

一般說明

磺酰罗丹明101是一种红色荧光染料，是水溶性的两性罗丹明。

應用

磺酰罗丹明101已用于：
  • 标记星形胶质细胞
  • 定量聚合酶链式反应(PCR)
  • 测定组织样品的损伤率

生化／生理作用

磺酰罗丹明101可特异性标记新皮质星形胶质细胞。常用于大脑成像。研究表明磺酰罗丹明101可用作癫痫引发药物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo
Nimmerjahn A, et al.
Nature Methods, 1(1), 31-31 (2004)
Florence Appaix et al.
PloS one, 7(4), e35169-e35169 (2012-04-18)
Fluorescent staining of astrocytes without damaging or interfering with normal brain functions is essential for intravital microscopy studies. Current methods involved either transgenic mice or local intracerebral injection of sulforhodamine 101. Transgenic rat models rarely exist, and in mice, a
In vivo imaging of oligodendrocytes with sulforhodamine 101
Hill RA and Grutzendler J
Nature Methods, 11(11), 1081-1081 (2014)
Danielle Tokarz et al.
PloS one, 12(10), e0186846-e0186846 (2017-10-25)
Osteocytes are the most abundant cell in the bone, and have multiple functions including mechanosensing and regulation of bone remodeling activities. Since osteocytes are embedded in the bone matrix, their inaccessibility makes in vivo studies problematic. Therefore, a non-invasive technique
Jumpei Ukita et al.
Scientific reports, 9(1), 3791-3791 (2019-03-09)
A comprehensive understanding of the stimulus-response properties of individual neurons is necessary to crack the neural code of sensory cortices. However, a barrier to achieving this goal is the difficulty of analysing the nonlinearity of neuronal responses. Here, by incorporating
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