跳转至内容
Merck
所有图片(3)

主要文件

查看所有文档

F6377

Sigma-Aldrich

荧光素 钠盐

Fluorescein sodium salt

Powder

别名:

D&C;黄色8号, 荧光素钠, 酸性黄 73

登录查看公司和协议定价
所有图片(3)

About This Item

经验公式（希尔记法）:
C20H10Na2O5
CAS号:
518-47-8
分子量:
376.27
颜色索引号:
45350
Beilstein:
3833041
EC 号:
208-253-0
MDL编号:
MFCD00167039
UNSPSC代码:
12171500
PubChem化学物质编号:
24894907
NACRES:
NA.47
价格与库存信息目前不能提供

产品名称

荧光素 钠盐, used as fluorescent tracer

质量水平

200

表单

powder

技术

titration: suitable

pH值（酸碱度）

8.3 (20 °C, 10 g/L)

mp

>300 °C

溶解性

H2O: 1 mg/mL

密度

0.78 g/cm3 at 29.6 °C (85.3 °F at 699.7 hPa)

荧光

λex 460 nm; λem 515 nm(lit.)

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

[Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2

InChI key

RGPLGPBQJOQFJS-UHFFFAOYSA-L

正在寻找类似产品? 访问 产品对比指南

相关类别

一般描述

荧光素是一种黄嘌呤染料，是生物学中常用的标记试剂。[1]

应用

水溶性荧光染料由于其分子半径小，渗透性和血管灌注研究中得到应用。[2] 以荧光素钠作为荧光示踪剂，用于研究血脑屏障(BBB)和血脊髓屏障(BSCB)在啮齿类动物模型中的通透性。[3][4][5] 以该染料为探针底物，研究了有机阴离子转运多肽(OATP)介导的肝细胞药物转运。[6]荧光素钠还被应用于光致退色后 原位 溶质通过荧光恢复进入骨内。[7]
荧光素钠盐被用作一种溶质，用于研究微血管渗透性。[8][9]它已被用作研究血液屏障穿透性的测试分子。[10]

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

423.7 °F - Pensky-Martens closed cup

闪点(°C)

217.6 °C - Pensky-Martens closed cup

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SHBS2708
SHBS3018
0000240645
0000150889
0000182362

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Liyun Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(33), 11911-11916 (2005-08-10)
Solute transport through the bone lacunar-canalicular system is believed to be essential for osteocyte survival and function but has proved difficult to measure. We report an approach that permits direct measurement of real-time solute movement in intact bones. By using
The determination of the conduction mechanism and optical band gap of fluorescein sodium salt.
Yakuphanoglu F, et al.
Physica B: Condensed Matter, 382(1), 21-25 (2006)
Advanced Fluorescence Reporters in Chemistry and Biology I: Fundamentals and Molecular Design (2010)
The acute and chronic toxicity of two xanthene dyes, fluorescein sodium salt and phloxine B, to Daphnia pulex.
Walthall WK and Stark JD.
Environmental Pollution (Barking, Essex : 1987), 104(2), 207-215 (1999)
Vascular endothelial growth factor enhances cancer cell adhesion to microvascular endothelium in vivo.
Shen S
Experimental Physiology, 95, 369-369 (2010)
查看所有相关文献
1 Review This action will navigate to reviews.

Questions

1–4 of 4 Questions  

  1. What is the purity of Fluorescein sodium salt (CAS number 518-47-8, article number F6377-100G)?

    1 answer

    1. This purity of this product is not determined.

      Helpful?

  2. Can this product be autoclaved once dissolved? How long can a concentrated dissolved stock solution be stored for?

    1 answer

    1. The stability of Fluorescein under autoclave conditions has not been determined. Solutions have typically been filter sterilized. Long term solution stability has also not been evaluated. However, solutions of Fluorescein Diacetate are stable at -20°C in ethanol when protected from light. Similar stability would be expected with the sodium salt form.

      Helpful?

  3. Hello, I am interested in Fluorescein or Fluoresein sodium salt to perform angiography in the living mouse and would like to know if your product has a pharmacological grade. Which product is used for angiography?

    1 answer

    1. Unfortunately, a pharmacological grade Fluorescein or Fluorescein sodium salt is not available at this time.

      Helpful?

  4. Is F6377 soluble in ethanol?

    1 answer

    1. The substance is soluble in water (500 g/l) at 20°C and slightly soluble in ethanol, but insoluble in benzene, chloroform, and ether.

      Helpful?

Reviews

Active Filters

  1. 1 Ratings-Only Review

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门