As reported in the 'DESCRIPTION' section of the product page, Sulfatide is a 3-O-sulfogalactosylceramide consisting primarily of galacto cerebroside sulfate. This product has not been further characterized.
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一般描述
硫苷脂(Sulfatide)是一种糖鞘脂,在宿主-病原体识别、β-细胞功能、感染、止血/血栓形成、蛋白运输、细胞生长、细胞黏附、神经可塑性、细胞形态发生与信号转导中起重要作用。[1][2]存在于各种血细胞表面,包括血小板、白细胞和红细胞。硫苷脂也存在于血清中,作为脂蛋白的糖鞘脂。[3]它由聚糖部分、疏水部分、3-O-硫酸半乳糖和神经酰胺组成,其中神经酰胺由鞘氨醇碱基和脂肪酸组成。[1]它是维持髓鞘和轴-胶连接正确形成的重要组分。硫苷脂的生产变异与癌症和免疫病等各种人类疾病有关。硫苷脂的代谢变化会导致突触功能障碍、神经功能减退、炎症和髓鞘恶化。[1]
硫苷脂是主要由半乳脑神经苷硫酸盐组成的 3-O-磺基半乳糖基神经酰胺。它位于髓鞘中,约占脑中总髓磷脂的 4%。[4]
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Sulfatide-binding assay for von Willebrand factor: detection of von Willebrand's disease without discrimination of vWD subtypes
Favaloro EJ
Thrombosis Research, 98(2), 213-219 (2000)
Quantification of sulfatides and lysosulfatides in tissues and body fluids by liquid chromatography tandem mass spectrometry
Mirzaian M, et al.
Journal of Lipid Research, 56(8), 936-943 (2015)
Age-and brain region-specific effects of dietary vitamin K on myelin sulfatides
Crivello NA, et al.
The Journal of Nutritional Biochemistry, 21(11), 1083-1088 (2010)
Maria Blomqvist et al.
Molecular and cellular neurosciences, 116, 103670-103670 (2021-09-26)
Sulfatide (3-O-sulfogalactosylceramide, SM4) is a glycosphingolipid, highly multifunctional and particularly enriched in the myelin sheath of neurons. The role of sulfatide has been implicated in various biological fields such as the nervous system, immune system, host-pathogen recognition and infection, beta
A recombinant two-module form of human properdin is an inhibitor of the complement alternative pathway
Kouser L, et al.
Molecular Immunology, 73(11), 76-87 (2016)
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Hi, Do you have any information about the sulfatide composition/profile of “Sulfatide from bovine brain (S1006)”.
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