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化驗
≥97% (TLC)
形狀
powder
儲存溫度
−20°C
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一般說明
A mixture of type I (containing α-hydroxy fatty acid) and type II (containing non-hydroxy fatty acid) cerebrosides. Galactocerebroside (GalCer) is a glycosphingolipid, that consists of a single galactose residue, connected to ceramide . GalCer is present within the exofacial leaflet of the lipid bilayer.
應用
Galactocerebrosides from bovine brain has been used to find the receptor activity of surface-immobilized galactosylceramide. It has also been used in sulfatide binding assay.
生化/生理作用
Galactocerebroside (GalCer) participates in the progression and maintenance of myelin. This oligodendroglial lipid is used as an immunohistochemical tool for studying oligodendrocytes.
Galactose linked to ceramide by a β-glycosidic linkage; the major lipid in adult brain, representing approximately 16% of total lipid; they are mainly localized to myelin and are markedly reduced in demyelinating diseases.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Piglet ileal mucus contains protein and glycolipid (galactosylceramide) receptors specific for Escherichia coli K88 fimbriae.
Infection and Immunity, 61(6), 2526-2531 (1993)
Oligodendrocyte morphology
Encyclopedia of Neuroscience (2009)
Scaffold-forming and adhesive contributions of synthetic laminin-binding proteins to basement membrane assembly
The Journal of Biological Chemistry, 284(13), 8984-8994 (2009)
Gangliosides and Autoimmune Peripheral Nerve Diseases
Progress in Molecular Biology and Translational Science, 156, 355-382 (2018)
The Journal of biological chemistry, 284(13), 8984-8994 (2009-02-05)
Laminins that possess three short arms contribute to basement membrane assembly by anchoring to cell surfaces, polymerizing, and binding to nidogen and collagen IV. Although laminins containing the alpha4 and alpha5 subunits are expressed in alpha2-deficient congenital muscular dystrophy, they
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