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Key Documents

RAB0286

Sigma-Aldrich

人IL-2 ELISA试剂盒

for serum, plasma, cell culture supernatant and urine

别名:

IL-1 beta, Interleukin-1 beta

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About This Item

分類程式碼代碼:
41116158
NACRES:
NA.32

物種活性

human

包裝

kit of 96 wells (12 strips x 8 wells)

技術

ELISA: suitable
capture ELISA: suitable

輸入

sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 2.07-1500 pg/mL

檢測方法

colorimetric

運輸包裝

wet ice

儲存溫度

−20°C

基因資訊

human ... IL2(3558)

一般說明

人 IL-2 ELISA(酶联免疫吸附测定)试剂盒采用体外酶联免疫吸附测定法,定量测定人血清、血浆、细胞培养物上清液和尿液中的 IL-2 含量。

免疫原

重组人 IL-2

應用

人IL-2 ELISA试剂盒已被用于分析人血浆中的干扰素水平。

生化/生理作用

IL-2(白介素 2)是由 T 细胞响应抗原或促有丝分裂刺激而产生的强效免疫调节淋巴因子。它是 I 型细胞因子。IL-2/IL-2R(白细胞介素 2/IL-2 受体)信号转导是 T 细胞增殖和免疫应答所必需的其他基本功能所必需的。IL-2 刺激 B 细胞、NK(自然杀伤)细胞、淋巴因子激活的杀伤细胞、单核细胞、巨噬细胞和少突胶质细胞的生长和分化。 与儿童复发性口腔溃疡、哮喘及 肺炎支原体感染有关。 小鼠体内 IL2 的缺失会引起致命的淋巴细胞增生性炎症疾病(IL-2 缺乏综合征)。IL-2 信号转导涉及三种途径:磷酸肌醇 3-激酶 (PI3-K)/AKT、Ras-MAPK(有丝分裂原活化蛋白激酶)和 JAK-STAT(Janus 激酶-信号转导子和转录激活子)途径。

其他說明

本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形圖

Corrosion

訊號詞

Warning

危險聲明

防範說明

危險分類

Met. Corr. 1

儲存類別代碼

8A - Combustible corrosive hazardous materials


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Placental trophoblast apoptosis is a major pathological feature of preeclampsia. Fas has been reported to be highly expressed in the placentas of patients with preeclampsia. However, the role and underlying mechanisms of Fas in the pathogenesis of preeclampsia have not
The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.
Bamford RN
Proceedings of the National Academy of Sciences of the USA, 91, 4940-4944 (1994)
IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation.
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Current Opinion in Immunology, 23, 598-604 (2011)
Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization.
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The Journal of Experimental Medicine, 201, 723-735 (2005)

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