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Merck

P9178

Sigma-Aldrich

Prochlorperazine dimaleate salt

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About This Item

经验公式(希尔记法):
C20H24ClN3S · 2C4H4O4
CAS号:
分子量:
606.09
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:
NACRES:
NA.77

形狀

powder

溶解度

H2O: slightly soluble 0.3 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.3 mg/mL
methanol: soluble

起源

GlaxoSmithKline

SMILES 字串

OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1

InChI

1S/C20H24ClN3S.2C4H4O4/c1-22-11-13-23(14-12-22)9-4-10-24-17-5-2-3-6-19(17)25-20-8-7-16(21)15-18(20)24;2*5-3(6)1-2-4(7)8/h2-3,5-8,15H,4,9-14H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-

InChI 密鑰

DSKIOWHQLUWFLG-SPIKMXEPSA-N

基因資訊

human ... DRD2(1813)

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生化/生理作用

Prochlorperazine is an anti-nausea and neuroleptic agent. It is known to cause neuropsychiatric side effects. Prochlorperazine inhibits the action of dopamine in the central nervous system. It acts as an antiemetic drug and prevents vomiting and stimulates sleep. Prochlorperazine is useful as a tranquilizer in the treatment of schizophrenia and nonpsychotic anxiety.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist; antispasmodic

特點和優勢

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

象形圖

Health hazardExclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Oral - Lact. - Repr. 2 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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