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![聚[d（I-C）] lyophilized, pkg of 10 U (10108812001 [A<sub>260</sub> units]), pkg of 50 U (11219847001 [A<sub>260</sub> units])](/deepweb/assets/sigmaaldrich/product/images/352/091/ef743cea-ccd8-44f1-8f3b-dec5a1e4f5d1/640/ef743cea-ccd8-44f1-8f3b-dec5a1e4f5d1.jpg)
应用
聚（脱氧肌苷 - 脱氧胞苷）酸钠盐已用于p65蛋白和neuro-2A蛋白裂解物的电泳迁移位移试验。它还被用作蛋白精氨酸甲基转移酶1（PRMT1）和DNA甲基转移酶1（DNMT1）选择性测定中的底物。
聚（脱氧肌苷 - 脱氧胞苷）酸钠盐已用于合成和表征双（2-（嘧啶-2-γl）乙氧基）烷烃及其药理活性的研究中。聚（脱氧肌苷 - 脱氧胞苷）酸钠盐也已用于研究碳酸钙薄膜在LB/LbL基质上生长。
聚（脱氧肌苷-脱氧胞苷）酸（聚（dI-dC）•聚（dI-dC））是可用作DNA底物的交替共聚物，其可用于评估DNA甲基转移酶（如DNA甲基转移酶1），以及作为双链DNA模型用于DNA结构动力学和药物、小分子、相互作用的构象研究。
生化/生理作用
聚（2′-脱氧肌苷-2′-脱氧胞苷酸），聚（dI-dC）是一种合成的DNA底物。在高盐下，Poly（dI-dC）以左旋螺旋构象存在，并在降低盐浓度过程中恢复为右旋形式。它可用于电泳迁移位移试验（EMSA）。
其他说明
双链交替共聚物
单位定义
在20mM磷酸钠/100mMNaCl(pH 7.0)缓冲液中，一个单位可在1.0ml中产生A260 = 1.0（1cm光程）
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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