P3635
5β-Pregnane-3α,20α-diol glucuronide
≥98.00% (TLC), powder, progesterone metabolite
别名:
P3G, PDG, Pn3-G, Pregnanediol-3a-glucuronide, Pregnanediol-glucuronide, 3α,20α-Dihydroxy-5β-pregnane 3-glucuronide
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所有图片(1)
About This Item
经验公式（希尔记法）:
C27H44O8
CAS号:
分子量:
496.63
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:
NACRES:
NA.77
推荐产品
product name
5β-Pregnane-3α,20α-diol glucuronide,
無菌
non-sterile
化驗
≥98.00% (TLC)
形狀
powder
技術
enzyme immunoassay: suitable
溶解度
ethanol: 20 mg/mL, clear, colorless
運輸包裝
ambient
儲存溫度
−20°C
SMILES 字串
CC(O)C1CCC2C3CCC4CC(CCC4(C)C3CCC12C)OC5OC(C(O)C(O)C5O)C(O)=O
InChI
1S/C27H44O8/c1-13(28)17-6-7-18-16-5-4-14-12-15(8-10-26(14,2)19(16)9-11-27(17,18)3)34-25-22(31)20(29)21(30)23(35-25)24(32)33/h13-23,25,28-31H,4-12H2,1-3H3,(H,32,33)
InChI 密鑰
ZFFFJLDTCLJDHL-UHFFFAOYSA-N
一般說明
5β-Pregnane-3α,20α-diol glucuronide is a progesterone metabolite predominant in urine, during pregnancy. Presence of 5β-Pregnane-3α,20α-diol glucuronide in the urine indicates pregnancy, but it might also account for pseudopregnancy. It is useful in predicting the delivery time/end of pseudopregnancy.
Urinary pregnanediol glucuronide (PdG) seems to serve as an effective clinical marker for monitoring progesterone supplementation. PdG, along with other urinary metabolites such as luteinizing hormone (LH), follicle stimulating hormone (FSH), and estrone glucuronide (ElG), exhibit a strong association with ovarian excretion rates and demonstrate a high correlation with serum reproductive hormones. As a result, they can be used interchangeably to effectively monitor ovarian steroidogenesis.
應用
5β-Pregnane-3α,20α-diol glucuronide has been used in a cross-sectional analysis of hormone levels. It has also been used as a standard to measure estradiol-17β, pregnanediol-glucuronide (PdG) by a double-antibody enzyme immunoassay.
5β-Pregnane-3α,20α-diol glucuronide has been used in steroid enzyme immunoassay.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Hormonal Smartphone Diagnostics
Matias-Garcia PR, et al.
Methods in Molecular Biology (2018)
Characterization of the ovarian cycle in the two-toed sloths (Choloepus didactylus): an innovative, reliable, and noninvasive method using fecal hormone analyses
Troll S, et al.
Theriogenology (2013)
Susanna J Park et al.
Fertility and sterility, 88(3), 684-690 (2007-04-17)
To define characteristics of the luteinizing hormone (LH) surge in urine. Observational study. Academic center. 46 women aged 20 to 35 years with regular menstrual cycles. Collected first morning urine daily, throughout one menstrual cycle. Urinary LH, follicle-stimulating hormone (FSH)
Jennifer E Mersereau et al.
Menopause (New York, N.Y.), 15(3), 482-486 (2008-01-19)
To compare daily reproductive hormone secretion in regularly menstruating older versus younger women. This was a prospective cohort study. Daily morning urine samples were obtained from 106 women, 28 of whom were aged between 20 and 34 years (mean: 27.8+/-3.7
Endocrine pregnancy monitoring in the two-toed sloth (Choloepus didactylus):?Pregnant or not pregnant?
Troll S, et al.
Theriogenology, 84(1), 137-144 (2015)
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