推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen ~19 kDa
种属反应性
rat, mouse
浓度
~2 mg/mL
技术
western blot: 0.5-1.0 μg/mL using rat brain (olfactory bulb) extract (S1 fraction).
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
rat ... Omp(24612)
一般描述
Olfactory marker protein (OMP) is a phylogenetically conserved, 19kDa, cytoplasmic protein of unknown function expressed almost exclusively in mature olfactory sensory neurons, in essentially all vertebrate species. The gene encoding OMP is localized on rat chromosome 1. OMP expression is initially detected in rat and mouse embryo during the last trimester of gestation and reaches adult levels at 2-4 weeks postnatally. It has been suggested that OMP is a novel modulatory component of the odor detection signal transduction cascade that is developmentally and physiologically regulated.
免疫原
synthetic peptide corresponding to amino acids 119-137 located near the C-terminus of rat OMP conjugated to KLH.
应用
Anti-OMP antibody produced in rabbit has been used in immunohistochemistry.
Anti-OMP antibody produced in rabbit has been used in:
- immunoblotting
- double immunofluorescence
- staining
生化/生理作用
Olfactory marker protein (OMP) helps to modulate the formation and refinement of the olfactory glomerular map. OMP-deficient mice generated by gene targeting in embryonic stem (ES) cells are compromised in their ability to respond to odor stimuli. In the OMP-null mouse, in addition to reduced odorant response, the levels of neural tyrosine hydroxylase (TH) and neuropeptide cholecystokinin (CCK) are severely reduced. It has been suggested that OMP is a novel modulatory component of the odor detection signal transduction cascade that is developmentally and physiologically regulated.
外形
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map
Albeanu DF, et al.
Nature Communications, 5073-5073 (2018)
Olfactory bulb increases marker protein in olfactory receptor cells
Chuah MI, et al.
The Journal of Neuroscience, 3(11), 2197-2205 (1983)
Yun-Feng Zhang et al.
iScience, 25(5), 104284-104284 (2022-05-20)
Self-grooming is a stereotyped behavior displayed by nearly all animals. Among other established functions, self-grooming is implicated in social communication. However, whether self-grooming specifically influences behaviors of nearby individuals has not been directly tested, partly because of the technical challenge
Cytotoxic effect of 5-bromo-2-deoxyuridine on olfactory epithelium
Raices M, et al.
MOJ proteomics & bioinformatics, 10-15406 (2015)
Analysis of chromosomal aberrations involving chromosome 1q31->q53 in a DMBA-induced rat fibrosarcoma cell line: Amplification and overexpression of Jak2
Sjoling A
Cytogenetics and Cell Genetics (2001)
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