跳转至内容
Merck

N7389

Sigma-Aldrich

3-硝基-L-酪氨酸

crystalline

登录查看公司和协议定价


About This Item

线性分子式:
O2NC6H3-4-(OH)CH2CH(NH2)CO2H
CAS号:
分子量:
226.19
Beilstein:
2813157
EC 号:
MDL编号:
UNSPSC代码:
12352200
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.32
价格与库存信息目前不能提供

表单

crystalline

mp

233-235 °C (dec.) (lit.)

SMILES字符串

N[C@@H](Cc1ccc(O)c(c1)[N+]([O-])=O)C(O)=O

InChI

1S/C9H10N2O5/c10-6(9(13)14)3-5-1-2-8(12)7(4-5)11(15)16/h1-2,4,6,12H,3,10H2,(H,13,14)/t6-/m0/s1

InChI key

FBTSQILOGYXGMD-LURJTMIESA-N

正在寻找类似产品? 访问 产品对比指南

相关类别

应用

3-硝基-L-酪氨酸已用于:
  • 蛋白质印迹分析,定量分析小鼠组织蛋白中的硝基酪氨酸水平[1][2]
  • Murashige–Skoog培养基,用于处理野生型和丝裂原活化蛋白激酶6 (mpk6)-2突变体幼苗,推断一氧化氮(NO)和MPK6在调节有丝分裂微管组织中的功能联系[3]
  • 免疫细胞化学[4]

生化/生理作用

3-硝基-L-酪氨酸是一种氧化剂和细胞毒剂。在全身性自免疫疾病患者体内,3-硝基酪氨酸可作为氮自由基改性蛋白质的生物标记物。它是过氧亚硝酸盐介导的氧化损伤的标志物。[5]硝基酪氨酸与乳腺癌患者体内的VEGF-C表达和淋巴结转移有关。3-硝基酪氨酸由氧化/亚硝化压力介导的化学改性(如在肺癌发生中观测到的蛋白质硝化)产生。[6]

相关产品

产品编号
说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Eman Ahmed Alaa El-Din et al.
Environmental science and pollution research international, 26(21), 21556-21564 (2019-05-28)
The evaluation of the toxicological effects of titanium dioxide nanoparticles (TiO2NPs) is increasingly important due to their growing occupational and industrial use. Curcumin is a yellow curry spice with a long history of use in herbal medicine and has numerous
Tzu-Hao Li et al.
Scientific reports, 6, 39405-39405 (2016-12-23)
Thalidomide can modulate the TNFα-NFκB and iNOS pathway, which involve in the pathogenesis of hepatopulmonary syndrome (HPS) and muscle wasting in cirrhosis. In bile duct ligated-cirrhotic rats, the increased circulating CD16+ (inflammatory) monocytes and its intracellular TNFα, NFκB, monocyte chemotactic
Ana C Andreazza et al.
Journal of neurochemistry, 127(4), 552-561 (2013-05-23)
Previously, we found decreased mitochondrial complex I subunits levels and increased protein oxidation and nitration in postmortem prefrontal cortex (PFC) from patients with bipolar disorder (BD) and schizophrenia (SCZ). The objectives of this study were to replicate our findings in
John Y Ng et al.
Open biology, 3(2), 120148-120148 (2013-02-08)
Protein 3-nitrotyrosine is a post-translational modification that commonly arises from the nitration of tyrosine residues. This modification has been detected under a wide range of pathological conditions and has been shown to alter protein function. Whether 3-nitrotyrosine is important in
Maren Carstensen et al.
European journal of clinical investigation, 43(4), 350-357 (2013-02-13)
Secreted frizzled-related protein 5 (Sfrp5) has been described as novel adipokine in mice with insulin-sensitising and anti-inflammatory properties similar to adiponectin. The aim of this study was to compare serum concentrations and determinants of Sfrp5, its pro-inflammatory antagonist wingless-type MMTV

Questions

Reviews

No rating value

Active Filters

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门