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Key Documents

L8039

Sigma-Aldrich

脂蛋白，高密度 来源于人类血浆

≥95% (SDS-PAGE), solution

别名:

α-脂蛋白, HDL, 高密度脂蛋白

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About This Item

CAS号:
308068-14-6
MDL號碼:
MFCD00164407
分類程式碼代碼:
12352211
NACRES:
NA.25

生物源

human plasma

品質等級

200

化驗

≥95% (SDS-PAGE)

形狀

solution

包裝

vial of 10 mg protein

技術

cell culture | mammalian: suitable

UniProt登錄號

P02649
P02655
P04114

官能基

ester
phospholipid

運輸包裝

wet ice

儲存溫度

2-8°C

基因資訊

human ... APOB(338) , APOC2(344) , APOE(348)

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相关类别

生化／生理作用

高密度脂蛋白（HDL）是胆固醇从血液、组织和器官转运到肝脏的转运剂，在肝脏中胆固醇会分解。 这个过程最终有助于清除动脉胆固醇。HDL俗称“好胆固醇”，占人体总胆固醇的20％-30％。

HDL用于心血管研究和开发潜在的心血管风险管理方法。

外觀

含150 mM NaCl和0.01% EDTA的溶液，pH 7.4

其他說明

有关脂蛋白功能和脂传递的更多信息，请见www.sigma-aldrich.com/enzymeexplorer

免責聲明

仅供研究使用。本品在法国的科研应用受到监管，包括用于进口和出口活动（法国《公共卫生法典》Public Health Code Article L 1211-1 paragraph 2）。如《公共卫生法典》所述，购买者（即最终用户）需要从法国研究部(France Ministry of Research)获得进口授权。订购此产品即代表您已确认获得合法的进口授权。

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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Santiago Redondo et al.
Lipids in health and disease, 10, 175-175 (2011-10-12)
Epidemiologic studies indicate a strong inverse correlation between plasma levels of high-density lipoproteins (HDL) and cardiovascular disease (CVD). The most relevant cardioprotective mechanism mediated by HDL is thought to be reverse cholesterol transport (RCT). New insights in HDL biology and
Kyung-Hyun Cho
Medicines (Basel, Switzerland), 8(7) (2021-08-07)
The composition and properties of apolipoprotein (apo) A-I and apoA-II in high-density lipoproteins (HDL) might be critical to SARS-CoV-2 infection via SR-BI and antiviral activity against COVID-19. HDL containing native apoA-I showed potent antiviral activity, while HDL containing glycated apoA-I
Tisha R Joy
Pharmacology & therapeutics, 135(1), 18-30 (2012-04-03)
Reduction in low-density lipoprotein cholesterol (LDL-C) levels has been associated with a 25-30% reduction in cardiovascular disease risk. However, there still remains a significant and quantifiable risk. Since epidemiologic data have demonstrated that low levels of high-density lipoprotein cholesterol (HDL-C)
Mark J Cziraky et al.
Journal of managed care pharmacy : JMCP, 14(8 Suppl), S3-28 (2009-11-07)
Most clinicians recognize the importance of reducing low-density lipoprotein cholesterol (LDL-C) and, therefore, address this therapeutic need to decrease cardiovascular disease risk. In addition to the critical role that LDL-C plays, recent studies have shown the contribution of other lipid
Joseph B Dubé et al.
Current opinion in lipidology, 23(2), 133-140 (2012-02-14)
Lipoprotein(a) [Lp(a)] is a risk factor for cardiovascular disease; we highlight the most recent research initiatives that have sought to define Lp(a)-dependent pathogenicity as well as pharmacologic approaches to lowering Lp(a). Recent large-scale meta-analyses have confirmed elevated Lp(a) concentrations to
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Cholesterol Transport

Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.

胆固醇的运输

由于胆固醇是水不溶性分子，必须包装后才能在血浆中运输。包装胆固醇、胆固醇酯和甘油三酯以便运输的颗粒称为脂蛋白。

Cholesterol Transport

Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.

Cholesterol Transport

Lipoproteins package cholesterol for transport in plasma, essential for lipid transport and cellular function in the body.

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