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L5501

Sigma-Aldrich

L -赖氨酸

≥98% (TLC), suitable for ligand binding assays

别名:

(S)-2,6-二氨基己酸

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About This Item

线性分子式:
H2N(CH2)4CH(NH2)CO2H
CAS号:
56-87-1
分子量:
146.19
Beilstein:
1722531
EC號碼:
200-294-2
MDL號碼:
MFCD00064433
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
24896404
NACRES:
NA.26
价格与库存信息目前不能提供

产品名称

L -赖氨酸, ≥98% (TLC)

品質等級

200

化驗

≥98% (TLC)

形狀

powder

技術

ligand binding assay: suitable

顏色

white to off-white

mp

215 °C (dec.) (lit.)

溶解度

H2O: soluble

SMILES 字串

NCCCC[C@H](N)C(O)=O

InChI

1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1

InChI 密鑰

KDXKERNSBIXSRK-YFKPBYRVSA-N

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一般說明

L-赖氨酸含有碱性侧链，是亲水性的。其侧链上的正丁基氨基在生理pH值下被质子化。降解后，L-赖氨酸产生酮体。赖氨酸与α-酮戊二酸酯的转胺反应生成乙酰乙酰辅酶A。[1][2]L-赖氨酸作为次生代谢产物的前体，如β-内酰胺抗生素。它也是合成α-氨基己二酸的前驱体。[3]

應用

L-赖氨酸是一种必需的蛋白原α氨基酸，其广泛用于各种应用。它已被用作：
  • 细胞培养基的一种补充物[4][5][6][7]
  • 以L-赖氨酸氧化酶(EC 1.4.3.14)等酶为底物
  • 作为多聚赖氨酸聚合物的组分
  • 作为聚赖氨酸聚合物的组成部分
  • 作为底物进行氧化和糖基化机理研究在钴赖氨酸的制备中[8][9]

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM1796
BCCM5272
BCCK1358
BCCJ7048
BCCH2019

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A L Leitão et al.
Applied microbiology and biotechnology, 56(5-6), 670-675 (2001-10-17)
In beta-lactam producing microorganisms, the first step in the biosynthesis of the beta-lactam ring is the condensation of three amino acid precursors: alpha-aminoadipate, L-cysteine and D-valine. In Nocardia lactamdurans and other cephamycin-producing actinomycetes, alpha-aminoadipate is generated from L-lysine by two
François-Michel Boisvert et al.
Molecular & cellular proteomics : MCP, 11(3), M111-M111 (2011-09-23)
Measuring the properties of endogenous cell proteins, such as expression level, subcellular localization, and turnover rates, on a whole proteome level remains a major challenge in the postgenome era. Quantitative methods for measuring mRNA expression do not reliably predict corresponding
Stryer L. and W. H. Freeman
Biochemistry (3rd Edition), 19-20 (1988)
Devlin T M
Textbook of Biochemistry: With Clinical Correlations (5th ed.), 97-97 (2002)
A D Springer et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 30(12), 1235-1242 (1982-12-01)
The introduction of heavy metals directly into living neuronal tissue has received little attention as a method for defining connections in the vertebrate nervous system. Procedures are described for the use of cobaltous-lysine to trace visual pathways with light microscopy.
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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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