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L1376

Sigma-Aldrich

亚油酸

≥98%

别名:

α亚油酸, 顺-9,顺-12-十八碳二烯酸

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About This Item

线性分子式:
CH3(CH2)4CH=CHCH2CH=CH(CH2)7CO2H
CAS号:
60-33-3
分子量:
280.45
Beilstein:
1727101
EC 号:
200-470-9
MDL编号:
MFCD00064241
UNSPSC代码:
12352211
PubChem化学物质编号:
24896279
NACRES:
NA.25
价格与库存信息目前不能提供

生物来源

plant oil (safflower)

质量水平

200

方案

≥98%

表单

liquid

颜色

colorless

折射率

n20/D 1.466 (lit.)

沸点

229-230 °C/16 mmHg (lit.)

mp

−5 °C (lit.)

密度

0.902 g/mL at 25 °C (lit.)

应用

life science and biopharma

官能团

carboxylic acid

脂质类型

omega FAs

运输

ambient

储存温度

−20°C

SMILES字符串

OC(CCCCCCC/C=C\C/C=C\CCCCC)=O

InChI

1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H,19,20)/b7-6-,10-9-

InChI key

OYHQOLUKZRVURQ-HZJYTTRNSA-N

基因信息

human ... SOAT1(6646) , SOAT2(8435)

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相关类别

一般描述

亚油酸是一种重要的膳食ω-6脂肪酸。它是细胞膜的结构成分。[1]

应用

亚油酸已用作测量脂氧合酶活性的底物。[2]它还用于制备亚油酸氢过氧化物样品，并研究柠檬酸盐稳定的CeO2的促氧化活性。[3]

生化/生理作用

亚油酸是一种n-6多不饱和必需脂肪酸(PUFA)，是花生四烯酸(AA)和多种前列腺素的前体。亚油酸可用于改善抗癌药物的给药和疗效，并用于癌症保护。亚油酸显著影响膜功能。[1]这种脂肪酸是生物活性代谢产物类花生酸的前体[2]，类花生酸调节肾肺功能、血管张力和炎症反应。[1]慢性脂肪吸收不良的婴儿会出现亚油酸缺乏。这种脂肪酸水平不足会导致婴儿生长发育不良、鳞状皮炎和免疫反应受损。亚油酸可保持皮肤水分含量，因此可用于局部涂敷。’[4]
在原代鸭肝细胞中，亚油酸可增加PPARα及其靶基因（如酰基辅酶A氧化酶）的细胞增殖和基因表达 [5]。

其他说明

如需了解生化试剂系列的更多信息，请填写此表。

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000428891
0000428890
0000428896
0000428889
0000428895

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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. I noticed it comes as a liquid. What does it coke dissolved in?

    1 answer

    1. This product is not diluted with any solvent. The physical form is a liquid. It is considered a 'neat' product with a minimum purity of 99%. The density is 0.902 g/mL at room temperature. The product is sold by weight, the 5 gram package would be approx. 5.5 mL.

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