I0160

亚胺培南 一水合物

≥98% (HPLC)

• 别名: Primaxin 一水合物, Tienam 一水合物, （5R，6S）-6-[（（1R）-1-羟基乙基] -3-[[2-[（亚氨基甲基）氨基]乙基]硫代] -7-氧代-1-氮杂双环[3.2.0] hept-2 -烯-2-羧酸 一水合物
• 经验公式（希尔记法）: C₁₂H₁₇N₃O₄S · H₂O
• CAS号: 74431-23-5
• 分子量: 317.36
• EC 号: 264-734-5
• MDL编号: MFCD09753321
• UNSPSC代码: 12352200
• PubChem化学物质编号: 329815301
• NACRES: NA.77

属性

• 方案: ≥98% (HPLC)
• 表单: powder
• 旋光性: [α]/D +73 to +84°, c = 0.5 in water
• 颜色: white to beige
• 溶解性: H₂O: >5 mg/mL
• 抗生素抗菌谱: mycobacteria
• 作用机制: cell wall synthesis | interferes
• 创始人: Merck & Co., Inc., Kenilworth, NJ, U.S.
• 储存温度: −20°C
• SMILES字符串: O.C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O
• InChI: 1S/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/m1./s1
• InChI key: GSOSVVULSKVSLQ-JJVRHELESA-N

说明

一般描述

Chemical structure: ß-lactam

应用

Imipenem monohydrate has been used to determine the resistance profiles of Pseudomonas aeruginosa isolates. It has also been used in susceptibility testing against Acinetobacter baumannii.

生化/生理作用

亚胺培南一水合物是广谱 B -内酰胺抗生素。

亚胺培南一水合物是广谱 B -内酰胺抗生素。 它是碳青霉烯类“魔弹”抗生素的一种，用于严重感染。

Imipenem is found effective against gram positive and negative aerobes and anaerobes. Imipenem is often combined with cilastatin, to inhibit its metabolism in kidney.

特点和优势

This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: Eyeshields, Gloves, type N95 (US)