G9880

谷丙转氨酶 来源于猪心脏

ammonium sulfate suspension, ≥75 units/mg protein

• 别名: L-丙氨酸:2-酮戊二酸氨基转移酶, GPT, 丙氨酸氨基转移酶（催化浓度）
• CAS号: 9000-86-6
• EC 号: 2.6.1.2 (BRENDA, IUBMB)
• Beilstein: 3562140
• EC 号: 232-561-4
• MDL编号: MFCD00131192
• UNSPSC代码: 12352204
• NACRES: NA.54

属性

• 生物来源: Porcine heart
• 质量水平: 200
• 表单: ammonium sulfate suspension
• 比活: ≥75 units/mg protein
• 分子量: 42 kDa
• 异质活性: L-glutamic dehydrogenase, lactic dehydrogenase and malic dehydrogenase ≤0.01%; glutamic-oxalacetic transaminase ≤0.05%
• 运输: wet ice
• 储存温度: 2-8°C

说明

一般描述

Research area: Cell Signaling
Glutamic-pyruvic transaminase (GPT) is located in most cells in the body but is found in highest concentrations in the liver. Two GPT isoforms, GPT1 and GPT2, are present in mammals.

应用

Glutamic-Pyruvic Transaminase from porcine heart has been used to determine L-lactate levels in aqueous polyethylene glycol (PEG) solutions.

生化/生理作用

GPT is responsible for catalyzing the reversible transamination of α-ketoglutarate and alanine to glutamate and pyruvate. It also plays a critical role in the metabolism of amino acids and gluconeogenesis.

谷丙转氨酶 (GPT) 存在于体内大多数细胞中，但在肝脏中浓度最高。由于在肝细胞坏死后 GPT 释放入血液，可作为肝脏疾病的标志物。

单位定义

一个单位在37℃和pH 7.6，L-丙氨酸存在条件下将1.0μmole α酮戊二酸转化成L-谷氨酸。

外形

1.8M (NH₄)₂SO₄ 溶液中的悬浮液，pH 6.0

分析说明

由缩二脲确定的蛋白质。

安全信息

• 象形图: GHS08
• 警示用语：: Danger
• 危险声明: H334
• 预防措施声明: P261 - P284 - P501
• 危险分类: Resp. Sens. 1
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: Eyeshields, Gloves, type N95 (US)