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Merck
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文件

G7879

Sigma-Aldrich

D-葡萄糖-6-磷酸 钠盐

≥98% (HPLC)

别名:

D(+)-葡糖醛糖6-磷酸 钠盐, G-6-P Na, 鲁氏酯

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About This Item

经验公式（希尔记法）:
C6H12NaO9P
CAS号:
54010-71-8
分子量:
282.12
Beilstein:
5787568
EC號碼:
258-921-0
MDL號碼:
MFCD00006611
分類程式碼代碼:
12352201
PubChem物質ID:
24895324
NACRES:
NA.25

生物源

synthetic (organic)

化驗

≥98% (HPLC)

形狀

crystalline

技術

HPLC: suitable

顏色

white

有用的pH值範圍

4.0-5.0

mp

204 °C (dec.) (lit.)

溶解度

water: 50 mg/mL, clear, colorless to very faintly yellow

正離子痕跡

Na: 6.1-10.2% (anhydrous)

儲存溫度

room temp

SMILES 字串

[Na+].O[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.Na/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;/h2-10H,1H2,(H2,11,12,13);/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1

InChI 密鑰

ZALKNDISPIVVKC-WYRLRVFGSA-M

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相关类别

應用

D-葡萄糖-6-磷酸钠可用作结核分枝杆菌的能源。

生化／生理作用

在细胞中，当葡萄糖被己糖激酶或葡萄糖激酶磷酸化，或在糖原分解过程中磷酸葡萄糖变位酶将 1-磷酸葡萄糖转化时，会生成 D-葡萄糖 6-磷酸（G6P）。G6P 位于糖酵解和磷酸戊糖途径的起始阶段。当血糖水平高时，它也可以作为糖原储存。

注意

与二钠盐不同，它不吸湿，并且在室温下对大气湿度非常稳定。

其他說明

为了全面了解我们针对客户研究提供的各种单糖产品，建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Iain J Abbott et al.
The Journal of antimicrobial chemotherapy, 75(4), 988-996 (2019-12-25)
To assess the antibacterial effects of a single 3 g oral fosfomycin dose on Escherichia coli and Klebsiella pneumoniae clinical isolates within a dynamic bladder infection model. An in vitro model simulating dynamic urinary fosfomycin concentrations was used. Target fosfomycin exposure
Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
There are limited treatment options for enterococcal urinary tract infections, especially vancomycin-resistant Enterococcus (VRE). Oral fosfomycin is a potential option, although limited data are available guiding dosing and susceptibility. We undertook pharmacodynamic profiling of fosfomycin against E. faecalis and E.
Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(3) (2020-01-08)
Oral fosfomycin trometamol is licensed as a single oral dose for the treatment of uncomplicated urinary tract infections, with activity against multidrug-resistant uropathogens. The impact of interindividual variability in urinary concentrations on antimicrobial efficacy, and any benefit of giving multiple
Iain J Abbott et al.
Journal of microbiological methods, 171, 105861-105861 (2020-02-09)
The impact of the bladder environment on fosfomycin activity and treatment response is uncertain. Standard laboratory media does not reflect the biomatrix of urine, where limited nutritional factors are important for growth and antimicrobial kill rates. We compared fosfomycin activity
Calvin S Carter et al.
Cell metabolism, 32(4), 561-574 (2020-10-08)
Aberrant redox signaling underlies the pathophysiology of many chronic metabolic diseases, including type 2 diabetes (T2D). Methodologies aimed at rebalancing systemic redox homeostasis have had limited success. A noninvasive, sustained approach would enable the long-term control of redox signaling for
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实验方案

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

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