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Merck
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文件

D3676

Sigma-Aldrich

10-脱乙酰基巴卡汀III 来源于浆果紫杉

≥95% (HPLC)

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About This Item

经验公式（希尔记法）:
C29H36O10
CAS号:
32981-86-5
分子量:
544.59
MDL號碼:
MFCD00132913
分類程式碼代碼:
51102829
PubChem物質ID:
24893778
NACRES:
NA.85

生物源

Taxus baccata

化驗

≥95% (HPLC)

形狀

solid

分子量

544.59 g/mol

顏色

white

溶解度

methanol: soluble, clear, colorless (5 mg + 0.1 mL MeOH)

抗生素活性譜

neoplastics

作用方式

DNA synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

[H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](O)C4=C(C)[C@@H](O)C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C

InChI

1S/C29H36O10/c1-14-17(31)12-29(36)24(38-25(35)16-9-7-6-8-10-16)22-27(5,23(34)21(33)20(14)26(29,3)4)18(32)11-19-28(22,13-37-19)39-15(2)30/h6-10,17-19,21-22,24,31-33,36H,11-13H2,1-5H3/t17-,18-,19+,21+,22-,24-,27+,28-,29+/m0/s1

InChI 密鑰

YWLXLRUDGLRYDR-ZHPRIASZSA-N

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應用

10-脱乙酰基浆果赤霉素III被用作制备抗癌药物紫杉醇（紫杉醇）的一种化学中间体。它被用于研究紫杉醇生物合成途径。

生化／生理作用

10-脱乙酰基浆果赤霉素III是紫杉醇生物合成的第五中间体。该生物合成通路由大约20个尚未被完全阐明的酶促步骤组成。

象形圖

Health hazardExclamation mark
GHS08,GHS07

訊號詞

Danger

危險分類

Carc. 1B - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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