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Merck
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Key Documents

B1814

Sigma-Aldrich

BMP2, human

Carrier Free, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

别名:

BMP-2

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.32

product name

Bone Morphogenetic Protein 2 human, Carrier Free, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

生物源

human

品質等級

重組細胞

expressed in E. coli

化驗

≥98% (SDS-PAGE)

形狀

lyophilized powder

分子量

26 kDa

包裝

pkg of 10 μg

儲存條件

avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)

技術

cell culture | mammalian: suitable

雜質

Endotoxin, tested

顏色

white

溶解度

water: soluble 0.100 mL, clear, colorless

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... BMP2(650)

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生化/生理作用

Cellular responses to BMP-2 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF-A by osteoblasts. Human, mouse, and rat BMP-2 demonstrate 100% homology.

外觀

Lyophilized from a 0.2 μm filtered buffered solution.

分析報告

The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 chondrogenic cells.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

104.0 °F - closed cup

閃點(°C)

40.0 °C - closed cup


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Ernst B Hunziker et al.
Tissue engineering. Part A, 21(13-14), 2089-2098 (2015-04-22)
The articular cartilage layer of synovial joints is commonly lesioned by trauma or by a degenerative joint disease. Attempts to repair the damage frequently involve the performance of autologous chondrocyte implantation (ACI). Healthy cartilage must be first removed from the
Lindsay A Bonsignore et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33(7), 979-987 (2015-02-14)
The most important factor contributing to short-term and long-term success of cementless total joint arthroplasties is osseointegration. Osseointegration leads to a direct structural and functional connection between living bone and the surface of an implant. Surface contaminants may remain on
Fengxuan Han et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 103(7), 1344-1353 (2014-11-12)
Repair of cartilage-bone interface tissue remains challenging, because it combines different cell types and gradients of composition and properties. To enable simultaneous regeneration of bone, cartilage, and especially their interface, a conically graded scaffold of chitosan-gelatin hydrogel/poly(l-lactide-co-glycolide) (PLGA) was facilely
Thorsten Pfirrmann et al.
Human molecular genetics, 24(11), 3119-3132 (2015-02-26)
Chordin-Like 1 (CHRDL1) mutations cause non-syndromic X-linked megalocornea (XMC) characterized by enlarged anterior eye segments. Mosaic corneal degeneration, presenile cataract and secondary glaucoma are associated with XMC. Beside that CHRDL1 encodes Ventroptin, a secreted bone morphogenetic protein (BMP) antagonist, the
Liping Wang et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33(8), 1212-1217 (2015-03-17)
Available evidence indicates that some Tie2-expressing (Tie2(+) ) cells serve as multipotent progenitors that have robust BMP-dependent osteogenic activity and mediate heterotopic ossification (HO). Since signaling through the G protein Gi is required for cell motility, we hypothesized that blockade

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