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Merck

A6376

Sigma-Aldrich

N-乙酰基-L-色氨酸

≥99% (TLC), suitable for ligand binding assays

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About This Item

经验公式(希尔记法):
C13H14N2O3
CAS号:
分子量:
246.26
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26
价格与库存信息目前不能提供

产品名称

N-乙酰基-L-色氨酸,

化驗

≥99% (TLC)

品質等級

形狀

powder

技術

ligand binding assay: suitable

顏色

white to off-white

儲存溫度

2-8°C

SMILES 字串

CC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI

1S/C13H14N2O3/c1-8(16)15-12(13(17)18)6-9-7-14-11-5-3-2-4-10(9)11/h2-5,7,12,14H,6H2,1H3,(H,15,16)(H,17,18)/t12-/m0/s1

InChI 密鑰

DZTHIGRZJZPRDV-LBPRGKRZSA-N

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生化/生理作用

N-乙酰基-L-色氨酸(NAT, Ac-Trp-OH)可用作底物PNK1速激肽受体拮抗剂。N-乙酰基-L-色氨酸也作为一种竞争性抑制剂,用于鉴定、区分和表征色氨酸酶。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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James J Donkin et al.
Journal of neurotrauma, 28(2), 217-224 (2010-12-24)
Previous studies have demonstrated that the compound N-acetyl-L-tryptophan (NAT) reduces brain edema and improves functional outcome following traumatic brain injury (TBI). In this study we examined whether this effect was mediated via the neurokinin-1 receptor, and whether there was an
Liqiong Fang et al.
Journal of chromatography. A, 1218(41), 7316-7324 (2011-09-10)
N-acetyltryptophan (NAT) has long been used as a stabilizer in some protein solutions, such as human serum albumin, to prevent oxidative protein degradation. However, the fate of NAT has not been discussed in literature. Two NAT degradation products have been
James J Donkin et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 29(8), 1388-1398 (2009-05-14)
Brain edema and swelling is a critical factor in the high mortality and morbidity associated with traumatic brain injury (TBI). Despite this, the mechanisms associated with its development are poorly understood and interventions have not changed in over 30 years.
Hassan Abdoul-Carime et al.
Journal of the American Chemical Society, 126(38), 12158-12161 (2004-09-24)
Secondary low-energy electrons are abundantly created during the early moments following the deposition of energy by radiation into cells. Here we show the ability of slow (<12 eV) electrons to effectively decompose gas-phase N-acetyl tryptophan (NAT) which can model a
Olga B Morozova et al.
The journal of physical chemistry. B, 112(9), 2747-2754 (2008-02-13)
The efficiency of the chemical pathway of DNA repair is studied by time-resolved chemically induced dynamic nuclear polarization (CIDNP) using the model system containing guanosyl base radicals, and tryptophan as the electron donor. Radicals were generated photochemically by pulsed laser

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