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Merck

A0138

Sigma-Aldrich

黄曲霉素 G1

from Aspergillus flavus

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About This Item

经验公式(希尔记法):
C17H12O7
CAS号:
分子量:
328.27
Beilstein:
1299768
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

生物源

Aspergillus flavus

品質等級

形狀

powder

儲存溫度

2-8°C

SMILES 字串

COc1cc2OC3OC=CC3c2c4OC(=O)C5=C(CCOC5=O)c14

InChI

1S/C17H12O7/c1-20-9-6-10-12(8-3-5-22-17(8)23-10)14-11(9)7-2-4-21-15(18)13(7)16(19)24-14/h3,5-6,8,17H,2,4H2,1H3

InChI 密鑰

XWIYFDMXXLINPU-UHFFFAOYSA-N

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一般說明

Aflatoxins are hepatotoxic metabolites, that are produced by molds, such as, Aspergillus flavus and Aspergillus parasiticus. They are naturally occurring poisonous carcinogens and the most widely known mycotoxins. They are associated with liver cancer and immune system suppression.

應用

Aflatoxin G1 from Aspergillus flavus has been used as a standard for the determination of aflatoxin in various samples.

生化/生理作用

Hepatocarcinogen. Food contaminant produced by Aspergillus flavus, a common soil fungus.

警告

可能致癌。

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Carc. 1B - Muta. 1B

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Review of past and present research on Aflatoxin in Uganda
Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens (2008)
Validation of simultaneous analysis method for determination of aflatoxins in olive oil by high performance liquid chromatographyfluorescence detector
Nabizadeh S, et al.
Journal of Food Safety and Hygiene, 1(2), 63-68 (2015)
The use of regenerated immunoaffinity columns for aflatoxins B1, B2, G1 and G2 in peanut confection
Iha Mh, et al.
Journal of Chromatography A, 1483, 1-7 (2017)
Review of past and present research on Aflatoxin in Uganda
Kaaya NA and Warren HL
African Journal of Food, Agriculture, Nutrition and Development, 5(1) (2005)
Haitao Shen et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(9), 3222-3228 (2012-06-20)
Our previous studies showed intragastric administration of Aflatoxin G(1) (AFG(1)) could induce lung adenocarcinoma, which derived from alveolar type II cells (AT-II cells). AT-II cells contribute to Aflatoxin B(1) (AFB(1)) metabolism and also serve as the potential progenitor cells for

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Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

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