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Merck
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文件

91C

Sigma-Aldrich

白细胞氯乙酸AS-D萘酚酯（特异性酯酶）试剂盒

别名:

Leder染色

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About This Item

分類程式碼代碼:
12352106
NACRES:
NA.47

描述

Kit formulated with all liquid reagents

品質等級

500

儲存期限

Expiry date on the label.

IVD

for in vitro diagnostic use

應用

hematology
histology

運輸包裝

wet ice

儲存溫度

2-8°C

應用

酯酶普遍存在于自然界中，其中包含了一系列不同的酶，均可作用于选定底物。使用91C 试剂盒可通过“特定酯酶”对萘酚AS-D氯乙酸盐进行酶促水解，从而释放出萘酚自由基化合物。它随后可与重氮基化合物进行偶联，在酶活性位点处形成带明显颜色的沉淀。这种酶通常被认为对粒细胞系的细胞具有特异性。也可用于检测外周血、骨髓或经石蜡包埋的组织切片中的中性粒细胞。

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书
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訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1 - Skin Sens. 1 - STOT RE 2 Oral - STOT SE 3

標靶器官

Kidney, Respiratory system

安全危害

EUH019

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

分析证书(COA)

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Ganesan Ramesh et al.
Kidney international, 65(2), 490-499 (2004-01-14)
Salicylate was recently shown to provide protection against cisplatin nephrotoxicity in rats. We have demonstrated that enhanced tumor necrosis factor-alpha (TNF-alpha) production mediates, in part, cisplatin nephrotoxicity. The purpose of this study was to determine if the protective effects of
Paramahamsa Maturu et al.
Translational oncology, 7(4), 484-492 (2014-06-28)
The role of inflammation in cancer has been reported in various adult malignant neoplasms. By contrast, its role in pediatric tumors has not been as well studied. In this study, we have identified and characterized the infiltration of various inflammatory
Vittoria Esposito et al.
American journal of physiology. Renal physiology, 304(4), F440-F450 (2012-12-14)
C/EBP homologous protein (CHOP) is an important mediator of endoplasmic reticulum (ER) stress-induced cell and organ injury. Here we show that lipopolysaccharide (LPS)-induced acute kidney injury (AKI) is associated with ER stress and elevated CHOP. We postulated that CHOP(-/-) mice
Tarek M El-Achkar et al.
American journal of physiology. Renal physiology, 295(2), F534-F544 (2008-05-23)
Tamm-Horsfall protein (THP) is a glycoprotein with unclear functions expressed exclusively in thick ascending limbs (TAL) of the kidney. Its role in ischemic acute kidney injury is uncertain, with previous data suggesting a possible negative effect by enhancing cast formation
Tarek M El-Achkar et al.
American journal of physiology. Renal physiology, 300(4), F999-1007 (2011-01-14)
Tamm-Horsfall protein (THP) is a glycoprotein expressed exclusively in thick ascending limbs (TAL) of the kidney. We recently described a novel protective role of THP against acute kidney injury (AKI) via downregulation of inflammation in the outer medulla. Our current
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