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Merck

89270

Sigma-Aldrich

胸苷

≥99.0% (HPLC)

别名:

1-(2-脱氧-β-D-呋喃核糖)-5-甲基尿嘧啶, 1-(2-脱氧-β-D-呋喃核糖)胸苷, 2′-脱氧胸苷, dT, 胸腺嘧啶核苷

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About This Item

经验公式(希尔记法):
C10H14N2O5
CAS号:
分子量:
242.23
Beilstein:
89285
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
PubChem物質ID:
NACRES:
NA.51

生物源

synthetic

化驗

≥99.0% (HPLC)

形狀

powder

光學活性

[α]20/D +19±1°, c = 1% in H2O

mp

185-190 °C
186-188 °C (lit.)

溶解度

hot water: 1 g/10 mL

SMILES 字串

CC1=CN([C@H]2C[C@H](O)[C@@H](CO)O2)C(=O)NC1=O

InChI

1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m0/s1

InChI 密鑰

IQFYYKKMVGJFEH-XLPZGREQSA-N

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應用

胸腺嘧啶已用于:
  • 培养人成纤维细胞系。
  • 体外伤口愈合试验。
  • 培养各种癌症细胞系。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Edward J Gane et al.
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Acid sphingomyelinase (aSMase) is a human enzyme that catalyzes the hydrolysis of sphingomyelin to generate the bioactive lipid ceramide and phosphocholine. ASMase deficiency is the underlying cause of the genetic diseases Niemann-Pick Type A and B and has been implicated
Anne P Bouvy et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 29(8), 1587-1597 (2014-04-29)
To evaluate the influence of induction therapy on Tregs we investigated their origin, kinetics and function in kidney transplant patients after treatment with T-cell depleting rabbit antithymocyte globulin (rATG) or IL-2 receptor antagonist basiliximab. Flow cytometry was used to study
Yee Suan Poo et al.
PLoS neglected tropical diseases, 8(12), e3354-e3354 (2014-12-05)
The recent epidemic of the arthritogenic alphavirus, chikungunya virus (CHIKV) has prompted a quest to understand the correlates of protection against virus and disease in order to inform development of new interventions. Herein we highlight the propensity of CHIKV infections
Helen Chen et al.
Cell cycle (Georgetown, Tex.), 13(14), 2248-2261 (2014-05-31)
Construction of a mitotic spindle requires biochemical pathways to assemble spindle microtubules and structural proteins to organize these microtubules into a bipolar array. Through a complex with dynein, the receptor for hyaluronan-mediated motility (RHAMM) cross-links mitotic microtubules to provide structural

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