跳转至内容
Merck
所有图片(1)

主要文件

69554

Sigma-Aldrich

肽聚糖 来源于枯草芽孢杆菌

别名:

PGN

登录查看公司和协议定价


About This Item

MDL编号:
UNSPSC代码:
41116134
NACRES:
NA.21
价格与库存信息目前不能提供

一般描述

肽聚糖。是一种生物聚合物,是革兰氏阳性菌细胞壁的主要成分。肽聚糖由 N -乙酰基葡糖胺和 N -乙酰基胞壁酸交替单位的碳水化合物骨架组成,并被 D -和 L -氨基酸修饰。 N -乙酰胞壁酸残基与寡肽交联。末端肽为 D -丙氨酸,但其他氨基酸以 D -异构体存在。

应用

肽聚糖可用于裂解酶(如裂解酶)的活性评估。建议使用浓度为 0.15-3μ 的肽聚糖g/ml,溶于水或缓冲液,在 450 nm 处测定。肽聚糖不溶解,但在水中产生混悬液。
肽聚糖可激活 Toll 样受体 2 (TLR2),TLR2 存在于哺乳动物细胞中以刺激淋巴细胞。也可作为 Poly (I:C) 的拮抗剂发挥作用。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Yichao Xie et al.
Fish & shellfish immunology, 106, 384-392 (2020-08-11)
Antimicrobial peptide (AMP) is a crucial component of the innate immune system in crustaceans. In mud crab, Scylla paramamosain, a commercially important species, a glycine-rich antimicrobial peptide (Spgly-AMP) gene was newly identified and putatively encoded a 26aa signal peptide and
Christian Stelter et al.
PloS one, 6(6), e20749-e20749 (2011-06-23)
Intestinal inflammation induces alterations of the gut microbiota and promotes overgrowth of the enteric pathogen Salmonella enterica by largely unknown mechanisms. Here, we identified a host factor involved in this process. Specifically, the C-type lectin RegIIIβ is strongly upregulated during
Qian Zhu et al.
Fish & shellfish immunology, 100, 9-17 (2020-03-05)
Interleukin (IL)-11 is a multifunctional cytokine that exerts a series of important immunomodulatory effects and exists in many tissues and cells. A 1106-bp nucleotide sequence representing the complete cDNA of IL-11 was obtained from large yellow croaker (Larimichthys crocea), containing
Angela Cuttitta et al.
Fish & shellfish immunology, 67, 86-94 (2017-06-06)
Gene family encoding allograft inflammatory factor-1 (AIF-1) is well conserved among organisms; however, there is limited knowledge in lower organisms. In this study, the first AIF-1 homologue from cnidarians was identified and characterised in the sea anemone Anemonia viridis. The
Yu-Yuan Chen et al.
PloS one, 9(12), e115232-e115232 (2014-12-18)
Invertebrates rely on an innate immune system to combat invading pathogens. The system is initiated in the presence of cell wall components from microbes like lipopolysaccharide (LPS), β-1,3-glucan (βG) and peptidoglycan (PG), altogether known as pathogen-associated molecular patterns (PAMPs), via

商品

Peptidoglycan structure: alternating GlcNAc and N-acetylmuramic acid cross-linked to peptides form the basic backbone.

Peptidoglycan structure: alternating GlcNAc and N-acetylmuramic acid cross-linked to peptides form the basic backbone.

肽聚糖(PGN)的基本结构含有N-乙酰葡糖胺(GlcNAc)与N-乙酰胞壁酸交替单元的碳水化合物主链,其中N-乙酰胞壁酸残基与肽交联。

Peptidoglycan structure: alternating GlcNAc and N-acetylmuramic acid cross-linked to peptides form the basic backbone.

查看所有结果

Questions

1–5 of 5 Questions  
  1. What is the method of preparation of Product 69554, Peptidoglycan?

    1 answer
    1. Peptidoglycan is made by fermentation and so it is from vegetative cell bacteria.  Peptidoglycan is from strain DSM 10.

      Helpful?

  2. What is the solubility of Product 69554, Peptidoglycan?

    1 answer
    1. Peptidoglycans are insoluble in all solvents.  To increase the recovery of solubility, let the peptidoglycan soak in an aqueous buffer for several hours or overnight.

      Helpful?

  3. Is Product 69554, Peptidoglycan, Gram positive or Gram negative?

    1 answer
    1. Peptidoglycan is Gram positive.

      Helpful?

  4. What is the molecular weight of Product 69554, Peptidoglycan?

    1 answer
    1. Unfortunately, we have no references reporting the molecular weight of peptidoglycan.  Because it is not soluble without destroying the original structure, the molecular weight can not be determined by suitable analytical methods (GPC, viscosity, light scattering).

      Helpful?

  5. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

Reviews

No rating value

Active Filters

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门