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Merck
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主要文件

52194

Sigma-Aldrich

四甲基罗丹明异硫氰酸盐-葡聚糖

average mol wt 500,000

别名:

TRITC-右旋糖酐 500, TRITC葡聚糖, TRITC-右旋糖酐

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About This Item

MDL编号:
MFCD00132418
UNSPSC代码:
12352116
NACRES:
NA.32

生物来源

synthetic

表单

powder or crystals

分子量

average mol wt 500,000

标记范围

0.001-0.008 mol/mol TRITC glucose

荧光

λex 550 nm; λem 575 nm±5 nm in 0.1 M Tris pH 8.0

应用

cell analysis

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相关类别

一般描述

四甲基罗丹明异硫氰酸酯-葡聚糖–也称为TRITC-Dextran或TRITC-Dextran 500，是一种荧光染料和一种新型药物。TRITC-Dextran的荧光活性可在555nm纳米下进行检测。TRITC-葡聚糖分子基于浓度梯度通过被动扩散在细胞中释放。

应用

异硫氰酸四甲基罗丹明-右旋糖酐 (TRITC-Dextran 500) 是一种荧光探针，用于研究细胞的通透性、吞噬作用和内吞作用等细胞过程以及研究生物分子传递机制。

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM8923
BCCK6389
BCCK0028
BCCH0185
BCCF7837

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Margaret Clarke et al.
Journal of cell science, 115(Pt 14), 2893-2905 (2002-06-26)
The vacuolar H(+)-ATPase (V-ATPase) is a multi-subunit enzyme that plays important roles in eukaryotic cells. In Dictyostelium, it is found primarily in membranes of the contractile vacuole complex, where it energizes fluid accumulation by this osmoregulatory organelle and also in
Thea van der Wijk et al.
The Journal of biological chemistry, 278(41), 40020-40025 (2003-07-23)
Osmotic swelling of Intestine 407 cells leads to an immediate increase in cell surface membrane area as determined using the fluorescent membrane dye FM 1-43. In addition, as measured by tetramethylrhodamine isothiocyanate (TRITC)-dextran uptake, a robust (>100-fold) increase in the
Alexa Patzelt et al.
Journal of controlled release : official journal of the Controlled Release Society, 246, 174-182 (2016-09-20)
More and more investigations confirm that nanoparticles are incapable of overcoming the intact skin barrier in vivo. Do nanoparticles still have a future in dermal drug delivery? Unlike many other topically applied substances, nanoparticles have not been reported to utilize
Ngo Bich Nga Nathalie Tran et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 116, 12-16 (2016-10-25)
Hair follicle research is currently focused on the development of drug-loaded nanocarriers for the targeting of follicular structures in the treatment of skin and hair follicle-related disorders. In the present study, a dual-label nanocarrier system was implemented in which FITC-labeled
Matthias Osswald et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 22(24), 6078-6087 (2016-08-16)
The role of blood-brain barrier (BBB) integrity for brain tumor biology and therapy is a matter of debate. We developed a new experimental approach using in vivo two-photon imaging of mouse brain metastases originating from a melanoma cell line to
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