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Merck
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Key Documents

355A-1

Sigma-Aldrich

GLUT1 Rabbit Polyclonal Antibody

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

100
500

共軛

unconjugated

抗體表格

Ig fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

形狀

buffered aqueous solution

物種活性

human

包裝

vial of 0.1 mL concentrate (355A-14)
vial of 0.5 mL concentrate (355A-15)
bottle of 1.0 mL predilute (355A-17)
vial of 1.0 mL concentrate (355A-16)
bottle of 7.0 mL predilute (355A-18)

製造商/商標名

Cell Marque

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

控制

colorectal carcinoma, mesothelioma

運輸包裝

wet ice

儲存溫度

2-8°C

視覺化

membranous

基因資訊

human ... SLC2A1(6513)

一般說明

Glucose transporter type I (GLUT1), a prototype member of GLUT superfamily, is a membrane-associated erythrocyte glucose transport protein. It is a major glucose transporter in the mammalian blood-brain barrier, and also mediates glucose transport in endothelial cells of the vasculature, adipose tissue, and cardiac muscle. GLUT1 is detectable in many human tissues including those of colon, lung, stomach, esophagus, and breast. GLUT1 is overexpressed in malignant cells and in a variety of tumors that include the breast, pancreas, cervix, endometrium, lung, mesothelium, colon, bladder, thyroid, bone, soft tissues, and oral cavity. Immunohistochemical detection of GLUT1 has been shown to discriminate between reactive mesothelium and malignant mesothelioma in more than one study.Anti-GLUT1 is also useful in distinguishing benign endometrial hyperplasia from atypical endometrial hyperplasia and adenocarcinoma.

品質


IVD

IVD

IVD

RUO

聯結

GLUT1 Positive Control Slides, Product No. 355S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外觀

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

準備報告

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他說明

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

法律資訊

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Alaa Afify et al.
Acta cytologica, 49(6), 621-626 (2006-02-03)
To evaluate the extent to which adenocarcinomas in body cavity fluids express GLUT-1 in comparison to currently available markers for adenocarcinomas. Archival paraffin-embedded cell blocks of serous fluids from 25 cases of benign effusions containing reactive mesothelial cells and 39
Value of immunohistochemical markers in differentiating benign from malignant mesothelial lesions
Acurio A, et al.
United States and Canadian Academy of Pathology Annual Meeting, 2008 null
Yasufumi Kato et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 20(2), 215-220 (2006-12-29)
The separation of benign reactive mesothelium (RM) from malignant mesothelial proliferation can be a major challenge. A number of markers have been proposed, including epithelial membrane antigen, p53 protein, and P-glycoprotein. To date, however, no immunohistochemical marker that allows unequivocal

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