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Merck

T8656

Sigma-Aldrich

硫脲

ACS reagent, ≥99.0%

别名:

Sulfourea, 硫代尿素

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About This Item

线性分子式:
NH2CSNH2
CAS号:
分子量:
76.12
Beilstein:
605327
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.21
价格与库存信息目前不能提供

等级

ACS reagent

质量水平

方案

≥99.0%

灼烧残渣

≤0.1% (as SO4)

缺失

≤0.5% loss on drying, 105°C, 2h

mp

170-176 °C (lit.)
174-177 °C

溶解性

H2O: passes test

官能团

amine
thiourea

SMILES字符串

NC(N)=S

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

基因信息

mouse ... Ephx2(13850)

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一般描述

硫脲是含尿素硫的类似物。[1]

应用

硫脲已用于:
  • 用作肝组织匀浆的裂解缓冲液组分[2]
  • 二维凝胶蛋白酪氨酸磷酸酶(PTP)测定所用的二维样品缓冲液[3]
  • 蛋白质提取补液缓冲液[4]

离液剂;强变性剂。增加蛋白质的溶解性和回收率

生化/生理作用

硫脲是过氧化物自由基的自由基清除剂。[2]其表现出了抑制脂质过氧化和紫外线(UV)诱导胶原交联的作用。硫脲可用作生长刺激剂,抑制植物芽休眠。目前确知其可用于治疗甲状腺功能亢进症。[1]

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Investigation of protein-tyrosine phosphatases by in-gel assays.
Markova B, et al.
Methods, 35(1), 22-27 (2005)
Mechanism of the reduction of methylene blue by thiourea in aqueous acidic medium
Osunlaja AA
International Journal of ChemTech Research, 4(2), 609-617 (2012)
Shrinivas Venkataraman et al.
Macromolecular rapid communications, 34(8), 652-658 (2013-03-14)
Readily water-soluble PEGylated amphiphiles containing bis-thiourea-based molecular recognition units at the interface of hydrophobic and hydrophilic blocks are developed. Self-assembly of these amphiphiles is found to be dependent on the exact chemical composition of the hydrophobic component. Elongated, spherical, and
Mireille Vonlanthen et al.
The Journal of organic chemistry, 78(8), 3980-3988 (2013-03-09)
Proof that sulfur is a viable reporting element for the development of fluorescent chemosensors for metal ions is presented. To date, the majority of metal-responsive fluorescent chemosensors have relied on metal-nitrogen coordination to provide a fluorescence response, most commonly by

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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