SMB01324

Cyclo(His-Pro)

• 别名: Cyclo(L-histidyl-L-proline), Cyclo(histidyl-proline), Cyclo(prolylhistidine), Histidylproline diketopiperazine, Histidylproline dioxopiperazine, CHP
• 经验公式（希尔记法）: C₁₁H₁₄N₄O₂
• CAS号: 53109-32-3
• 分子量: 234.25
• MDL號碼: MFCD00133207
• 分類程式碼代碼: 12352209
• NACRES: NA.26

属性

• 化驗: 98% (HPLC)
• 品質等級: 100
• 形狀: solid
• 顏色: white to off-white
• mp: 162—164 °C
• 運輸包裝: 2-8°C
• 儲存溫度: −20°C
• SMILES 字串: O=C1N[C@@H](Cc2cnc[nH]2)C(=O)N3CCC[C@@H]13
• InChI: 1S/C11H14N4O2/c16-10-9-2-1-3-15(9)11(17)8(14-10)4-7-5-12-6-13-7/h5-6,8-9H,1-4H2,(H,12,13)(H,14,16)/t8-,9-/m0/s1
• InChI 密鑰: NAKUGCPAQTUSBE-IUCAKERBSA-N

说明

一般說明

Cyclo(His-Pro) is a cyclic dipeptide consisting of the amino acids histidine (His) and proline (Pro). This small peptide forms a closed loop, with histidine and proline connected through a peptide bond. It can be found naturally in certain proteins and peptides and can also be synthesized chemically. This unique molecule is related to thyrotropin-releasing hormone and has various roles in the central nervous system. It serves as a substrate for organic cation transporters, making it essential for neuroprotection. Cyclo(His-Pro) holds promise for therapeutic applications, with the potential to counteract neuroinflammation-based degenerative conditions through both oral and parenteral administration routes. It can inhibit NF-κB nuclear accumulation and influence a range of inflammatory and stress responses, making it a valuable asset in the study of cell biology, biochemical research, and neuroprotection research.

應用

Cyclo(L-His-L-Pro) is a versatile molecule and it finds application in biochemical and metabolomics research.

特點和優勢

• Can be used in Metabolomics and Biochemical research
• High-quality compound suitable for multiple research applications

其他說明

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安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3