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LIGHTOX19

Sigma-Aldrich

LightOx™19

≥95% (HPLC)

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About This Item

经验公式（希尔记法）:
C23H23NO2
CAS号:
2324152-25-0
分子量:
345.43
UNSPSC代码:
12352101
NACRES:
NA.22

方案

≥95% (HPLC)

表单

powder

储存温度

2-8°C

SMILES字符串

N1(c2c(cc(cc2)C#Cc3ccc(cc3)C(=O)O)C(C=C1)(C)C)C(C)C

InChI key

HXWVRWZLWIKKOS-UHFFFAOYSA-N

相关类别

应用

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

生化/生理作用

Strong ligand for retinoic acid receptor proteins

特点和优势

LightOx19 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx19 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

其他说明

Chemical Equivalency 1ea=1mg

法律信息

LightOx is a trademark of LightOx Ltd.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Fluorescent Retinoid Probes

Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.

Fluorescent Retinoid Probes

Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.

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