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LIGHTOX21

Sigma-Aldrich

LightOx™21

≥95% (HPLC)

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About This Item

经验公式（希尔记法）:
C21H21NO2
CAS号:
2342579-16-0
分子量:
319.40
分類程式碼代碼:
12352101
NACRES:
NA.22

應用

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

生化／生理作用

Strong ligand for retinoic acid receptor proteins

特點和優勢

LightOx21 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx21 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

其他說明

Chemical Equivalency 1ea=1mg

法律資訊

LightOx is a trademark of LightOx Ltd.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析证书(COA)

Lot/Batch Number

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Fluorescent Retinoid Probes

Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.

Fluorescent Retinoid Probes

Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.

Fluorescent Retinoid Probes

Fluorescent retinoic acid analogues for use in cellular imaging, protein-ligand binding assays, and flow cytometry to bypass traditional problems associated with fluorescent probes.

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