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Merck

E4009

Sigma-Aldrich

伊红 Y

Dye content ~99%, Powder

别名:

2′,4′,5′,7′-四溴荧光素, 四溴荧光黄, 曙红 Y, 曙红微黄, 溶剂红 43, 酸性红 87, 醇溶伊红

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About This Item

经验公式(希尔记法):
C20H8Br4O5
CAS号:
分子量:
647.89
顏色索引編號:
45380:2
EC號碼:
MDL號碼:
分類程式碼代碼:
12171500
PubChem物質ID:
NACRES:
NA.47
价格与库存信息目前不能提供

产品名称

伊红 Y, Dye content ~99 %

形狀

powder

品質等級

成份

Dye content, ~99%

顏色

light red to red/pink

溶解度

ethanol: 1 mg/mL

應用

diagnostic assay manufacturing
hematology
histology

儲存溫度

room temp

SMILES 字串

Oc1c(Br)cc2c(Oc3c(Br)c(O)c(Br)cc3C24OC(=O)c5ccccc45)c1Br

InChI

1S/C20H8Br4O5/c21-11-5-9-17(13(23)15(11)25)28-18-10(6-12(22)16(26)14(18)24)20(9)8-4-2-1-3-7(8)19(27)29-20/h1-6,25-26H

InChI 密鑰

DBZJJPROPLPMSN-UHFFFAOYSA-N

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應用

曙红Y可用作以下应用的染色剂:
  • 确定脑切片位置[1]
  • 染色固定肝脏组织[2]
  • 组织学检验背侧海马体脑来源切片[3]

生化/生理作用

曙红Y是一种呫吨染料,用于连接组织和细胞质的差别染色。在组织病理学中,它用在苏木精之后,甲基蓝之前作为复染。它也可作为背景染色,为细胞核然和提供反差。[4][5]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats.
Sun J, et al.
International Journal of Molecular Medicine, 30, 739-739 (2012)
Inactivation of NF-kappaB p50 leads to insulin sensitization in liver through post-translational inhibition of p70S6K.
Gao Z, et al.
The Journal of Biological Chemistry, 284, 18368-18368 (2009)
Antonello Mai et al.
Journal of medicinal chemistry, 51(7), 2279-2290 (2008-03-20)
A number of new compounds bearing two ortho-bromo- and ortho, ortho-dibromophenol moieties linked through a saturated/unsaturated, linear/(poly)cyclic spacer (compounds 1- 9) were prepared as simplified analogues of AMI-5 (eosin), a recently reported inhibitor of both protein arginine and histone lysine
An immunohistochemical analysis of SERT in the blood-brain barrier of the male rat brain.
Young LW, et al.
Histochemistry and Cell Biology, 144, 321-321 (2015)
Florian Ménard et al.
Bioorganic & medicinal chemistry, 17(22), 7647-7657 (2009-10-13)
This paper reports the synthesis and characterization of a new class of tetrabenzoporphyrins bearing glucosyl or polyamine units on meso positions to improve the targeting of cancer cells. Photocytotoxic activity of these photosensitizers was tested on cell lines HaCaT and

Questions

1–2 of 2 Questions  
  1. What is the purity level for product E4009 and can it be added to CoA?

    1 answer
    1. t is not possible to add a purity specification to Eosin Y free acid because no purity tests are performed

      Helpful?

  2. Is there a sample protocol for this product ? There id low solubility of E4009 in even ethanol (1 mg/mL) in that case how to make the usual eosin concentration of 1-5% w/v for use in an H&E staining reaction.

    1 answer
    1. It is not feasible to dissolve catalog number E4009 to a concentration of 1 to 5% in alcohol. For H&E staining or staining sperm for viability, Eosin Y disodium salt is typically used, rather than Eosin Y free acid. Dry dyes, available under catalog numbers E4382 or 861006, are also used, along with various solutions for H&E staining, which also utilize only Eosin Y disodium salt. A 5% Eosin Y solution is available with the catalog number 318906, which is also formulated with Eosin Y disodium salt.

      Helpful?

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