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Merck

BP460

烟酰胺

British Pharmacopoeia (BP) Reference Standard

别名:

吡啶-3-甲酰胺, 烟碱酰胺, 烟酰胺, 维生素 B3, 维生素 PP

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About This Item

经验公式(希尔记法):
C6H6N2O
CAS号:
分子量:
122.12
Beilstein:
383619
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

pharmaceutical primary standard

agency

BP

API 家族

nicotinamide

形狀

solid

製造商/商標名

BP

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

128-131 °C (lit.)

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

−20°C

SMILES 字串

NC(=O)c1cccnc1

InChI

1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)

InChI 密鑰

DFPAKSUCGFBDDF-UHFFFAOYSA-N

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一般說明

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Nicotinamide, a member of the family of water-soluble B vitamins, is generally produced from nicotinic acid (vitamin B3). It is often present in food products. It has been reported to have been effective in the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It is also shown to possess anti-inflammatory activity.

應用

Nicotinamide BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Vitamins B and C Injection
  • Nicorandil Tablets
  • 生化/生理作用

    烟酰胺是维生素B3的酰胺衍生物,是PARP抑制剂

    包裝

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    其他說明

    Sales restrictions may apply.

    象形圖

    Exclamation mark

    訊號詞

    Warning

    危險聲明

    危險分類

    Eye Irrit. 2

    儲存類別代碼

    11 - Combustible Solids

    水污染物質分類(WGK)

    WGK 1

    閃點(°F)

    302.0 °F - closed cup

    閃點(°C)

    150 °C - closed cup


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    分析证书(COA)

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    访问文档库

    Evaluation of analytical tools and multivariate methods for quantification of co-former crystals in ibuprofen-nicotinamide co-crystals
    Soares FLF and Carneiro RL
    Journal of Pharmaceutical and Biomedical Analysis, 89, 166-175 (2014)
    Development of a validated HPLC method for the determination of B-complex vitamins in pharmaceuticals and biological fluids after solid phase extraction
    Chatzimichalakis PF, et al.
    Journal of Separation Science, 27(14), 1181-1188 (2004)
    Nicotinamide
    European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
    European pharmacopoeia, 14(4), 3145-3146 (2017)
    Simultaneous determination and classification of riboflavin, thiamine, nicotinamide and pyridoxine in pharmaceutical formulations, by UV-visible spectrophotometry and multivariate analysis
    Lopez-de-Alba LP, et al.
    Journal of the Brazilian Chemical Society, 17(4), 715-722 (2006)
    Youdan Shi et al.
    International immunopharmacology, 14(4), 530-537 (2012-10-13)
    Nicotinamide (NAM), the amide form of vitamin B3, is involved in a wide range of biological processes. Recent evidence revealed the anti-inflammatory and anti-oxidant properties of NAM and suggests it may be used as a novel strategy in the prevention

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