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A3648

Sigma-Aldrich

(3-氨基丙基)三乙氧基硅烷

≥98%

别名:

APTS, 3-氨丙基三乙氧基硅烷, APTES

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About This Item

线性分子式:
H2N(CH2)3Si(OC2H5)3
CAS号:
919-30-2
分子量:
221.37
Beilstein:
1754988
EC 号:
213-048-4
MDL编号:
MFCD00008207
UNSPSC代码:
12171500
PubChem化学物质编号:
24890794
NACRES:
NA.47
价格与库存信息目前不能提供

质量水平

200

方案

≥98%

表单

liquid

pH值（酸碱度）

11 (20 °C, 20 g/L)

沸点

217 °C/760 mmHg (lit.)

mp

220-222 °C

密度

0.946 g/mL at 25 °C (lit.)

应用

diagnostic assay manufacturing
hematology
histology

储存温度

room temp

SMILES字符串

CCO[Si](CCCN)(OCC)OCC

InChI

1S/C9H23NO3Si/c1-4-11-14(12-5-2,13-6-3)9-7-8-10/h4-10H2,1-3H3

InChI key

WYTZZXDRDKSJID-UHFFFAOYSA-N

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应用

  • （3-氨基丙基）三乙氧基硅烷已用于制备玻片上的钙粘蛋白表面。[1]
  • 它已用于制备RGD（Arg-Gly-Asp）处理的有机硅膜。[2]
  • 它已用于制备亲和素-生物素盖玻片。[3]

生化/生理作用

（3-氨基丙基）三乙氧基硅烷可形成玻璃的氨基丙基衍生物，一种用于亲和色谱的吸附剂。它用于制备适合用于各种免疫组化和原位杂交过程的带正电荷的玻片。[4]

象形图

CorrosionExclamation mark
GHS05,GHS07

警示用语：

Danger

危险声明

H302,H314,H317

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 1

闪点(°F)

199.4 °F - closed cup

闪点(°C)

93 °C - closed cup

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
WXBF5027V
WXBF4299V
WXBF3409V
WXBF3660V
WXBF2194V

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Apoptosis and survival of osteoblast-like cells are regulated by surface attachment.
Grigoriou V, et al.
The Journal of Biological Chemistry, 280, 1733-1739 (2005)
Real-time observation of a single DNA digestion by lambda exonuclease under a fluorescence microscope field.
Matsuura S, et al.
Nucleic Acids Research, 29, E79-E79 (2001)
Dan Zheng et al.
Talanta, 99, 22-28 (2012-09-13)
A mediatorless glucose biosensor was developed by the immobilization of glucose oxidase (GOx) to graphene-functionalized glassy carbon electrode (GCE). The surface of GCE was functionalized with graphene by incubating it with graphene dispersed in 3-aminopropyltriethoxysilane (APTES), which acted both as
Vladimir Gubala et al.
Analytica chimica acta, 760, 75-82 (2012-12-26)
Herein a simple analytical method is presented for the characterization of biomolecule adsorption on cyclo olefin polymer (COP, trade name: Zeonor(®)) substrates which are widely used in microfluidic lab-on-a-chip devices. These Zeonor(®) substrates do not possess native functional groups for
Peng Yuan et al.
Nanotechnology, 23(37), 375705-375705 (2012-08-28)
The surfaces of naturally occurring halloysite nanotubes were functionalized with γ-aminopropyltriethoxysilane (APTES), which was found to have a substantial effect on the loading and subsequent release of a model dye molecule. APTES was mostly anchored at the internal lumen surface
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Questions

1–6 of 6 Questions  

  1. How does Product A3648, (3-Aminopropyl)triethoxysilane, compare to poly-L-lysine for binding tissue to glass surfaces?

    1 answer

    1. This product has been cited as being a better tissue adhesive than poly-L-lysine. Maddox PH, Jenkins D., 3-Aminopropyltriethoxysilane (APES): a new advance in section adhesion. J Clin Pathol., 40(10):1256-7 (1987).

      Helpful?

  2. Can the coating made from product A3648, (3-Aminopropyl)triethoxysilane, be removed?

    1 answer

    1. For Product A3648, (3-Aminopropyl)triethoxysilane, the siliconized coating can be removed by an overnight treatment with 10-20% (w/v) aqueous or alcoholic potassium hydroxide or sodium hydroxide solutions. It may also be possible to remove the coating by physical abrasion, i.e., scrubbing or vigorously brushing the glass surface. Autoclaving will not destroy the coating.

      Helpful?

  3. What is the concentration of the (3-Aminopropyl)triethoxysilane, commonly known as APTES?

    1 answer

    1. The (3-Aminopropyl)triethoxysilane, which is a neat liquid, is 4.3 M. This is based on a density of 0.946 g/mL and a molecular weight of 221.37.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  5. Can I buy glass slides already treated with Product A3648, (3-Aminopropyl)triethoxysilane?

    1 answer

    1. Yes. Silane Prep slides, Product No. S4651, are produced using A3648. These slides have an expiration period of 24 months.

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  6. Can Product A3648, (3-Aminopropyl)triethoxysilane, be used to coat controlled pore glass?

    1 answer

    1. To coat controlled-pore glass beads for affinity chromatography, the following method is recommended:1. Treat 1 g of clean beads with 20 mL of a 10% aqueous A3648 (pH 3 to 4) at 75 °C for 2 hours.2. Filter the beads to remove the solution and dry overnight in a 115 °C oven. See: J. Dairy Sci., 73, 2720-2730 (1990).

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