推荐产品
等级
analytical standard
质量水平
方案
≥98.5% (HPLC)
保质期
limited shelf life, expiry date on the label
技术
HPLC: suitable
gas chromatography (GC): suitable
杂质
≤12.0% water
应用
forensics and toxicology
pharmaceutical (small molecule)
包装形式
neat
储存温度
2-8°C
SMILES字符串
O[C@@H]1[C@@H](O)[C@H](OC2=CC=C(NC(C)=O)C=C2)O[C@H](C(O)=O)[C@H]1O
InChI
1S/C14H17NO8/c1-6(16)15-7-2-4-8(5-3-7)22-14-11(19)9(17)10(18)12(23-14)13(20)21/h2-5,9-12,14,17-19H,1H3,(H,15,16)(H,20,21)/t9-,10-,11+,12-,14+/m0/s1
InChI key
IPROLSVTVHAQLE-BYNIDDHOSA-N
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
其他客户在看
Carolina I Ghanem et al.
Biochemical pharmacology, 77(10), 1621-1628 (2009-05-12)
Development of resistance to toxic effects of acetaminophen (APAP) was reported in rodents and humans, though the mechanism is only partially understood. We examined in rats the effect of administration with subtoxic daily doses (0.2, 0.3, and 0.6g/kg, i.p.) of
Nicole J Barshop et al.
Journal of pediatric gastroenterology and nutrition, 52(2), 198-202 (2011-01-18)
: The aim of the study was to evaluate UDP-glucuronyltransferase activity and the pharmacokinetics of a single oral dose of acetaminophen (APAP) in children with nonalcoholic fatty liver disease (NAFLD). : Twelve boys 10 to 17 years old with biopsy-proven
Sifeng Mao et al.
Lab on a chip, 12(1), 219-226 (2011-11-19)
In this work, we developed a microfluidic device for the imitation of drug metabolism in human liver and its cytotoxicity on cells. The integrated microfluidic device consists of three sections: (1) bioreactors containing poly(ethylene) glycol (PEG) hydrogel encapsulated human liver
Michael Ganetsky et al.
Journal of clinical pharmacology, 53(4), 413-420 (2013-02-26)
Acetaminophen poisoning is the most frequent cause of acute hepatic failure in the US. Toxicity requires reductive metabolism of acetaminophen, primarily via CYP2E1. Liquid acetaminophen preparations contain propylene glycol, a common excipient that has been shown to reduce hepatocellular injury
Marie Lecoeur et al.
Talanta, 205, 120108-120108 (2019-08-28)
In this study, a capillary electrophoresis-tandem mass spectrometry method combining efficient separation and sensitive detection has been developed and validated, for the first time, to quantify acetaminophen and five of its metabolites in urine samples. Optimization of the method has
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