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Merck

35032

Supelco

芬苯达唑

VETRANAL®, analytical standard

别名:

5-苯硫基苯并咪唑-2-氨基甲酸甲酯

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About This Item

经验公式(希尔记法):
C15H13N3O2S
CAS号:
分子量:
299.35
Beilstein:
759077
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24
价格与库存信息目前不能提供

等级

analytical standard

质量水平

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

clinical testing

包装形式

neat

SMILES字符串

COC(=O)Nc1nc2cc(Sc3ccccc3)ccc2[nH]1

InChI

1S/C15H13N3O2S/c1-20-15(19)18-14-16-12-8-7-11(9-13(12)17-14)21-10-5-3-2-4-6-10/h2-9H,1H3,(H2,16,17,18,19)

InChI key

HDDSHPAODJUKPD-UHFFFAOYSA-N

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一般描述

Chemical structure: benzimidazole
Fenbendazole is a thio substituted benzimidazole, which belongs to the group of anthelmintics.[1] It can be widely used in veterinary medicine particularly, in the treatment of helminth infections.[2]

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

相关产品

产品编号
说明
价格

象形图

Health hazardEnvironment

警示用语:

Warning

危险声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2

靶器官

Liver,lymph node,Stomach,Nervous system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Determination of fenbendazole and oxfendazole in liver and muscle using liquid chromatography?mass spectrometry
Blanchflower J.W, et al.
Analyst, 119, 1325-1328 (1994)
Interaction between fenbendazole and piperonyl butoxide: pharmacokinetic and pharmacodynamic implications
Benchaoui.A.H and Mckellar.A.Q
The Journal of Pharmacy and Pharmacology, 48, 753-759 (1996)
C Chassaing et al.
Journal of medicinal chemistry, 51(5), 1111-1114 (2008-02-15)
Highly water-soluble prodrugs 1a- g of anthelmintic benzimidazole carbamates 2a- g were synthesized. These prodrugs combine high aqueous solubility and stability with high lability in the presence of alkaline phosphatases. The veterinary utility of 1a was shown by a pharmacodynamic
Nilambra Dogra et al.
The Journal of biological chemistry, 287(36), 30625-30640 (2012-06-30)
In recent years, there has been a great deal of interest in proteasome inhibitors as a novel class of anticancer drugs. We report that fenbendazole (FZ) (methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl)carbamate) exhibits a potent growth-inhibitory activity against cancer cell lines but not normal
Niels C Kyvsgaard et al.
Veterinary parasitology, 181(2-4), 248-254 (2011-05-17)
Horses, mules and donkeys are indispensable farming and working animals in many developing countries, and their health status is important to the farmers. Strongyle parasites are ubiquitous in grazing horses world-wide and are known to constitute a threat to equine

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