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158127

Sigma-Aldrich

多聚甲醛

powder, 95%

别名:

聚氧亚甲基

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About This Item

线性分子式:
HO(CH2O)nH
CAS号:
30525-89-4
分子量:
30.03 (as monomer)
MDL编号:
MFCD00133991
UNSPSC代码:
12352100
PubChem化学物质编号:
24849719
NACRES:
NA.21
价格与库存信息目前不能提供

蒸汽密度

1.03 (vs air)

质量水平

200

蒸汽压

<1.45 mmHg ( 25 °C)

方案

95%

表单

powder

自燃温度

572 °F

expl. lim.

73 %

mp

120-170 °C (lit.)

密度

0.88 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

[O-]#[C+H2]

InChI

1S/CH2O/c1-2/h1H2

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

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一般描述

多聚甲醛又称聚甲醛。其作为外部CO源参与芳香醛和酯的合成。[1]

其他说明

2024年CiteAb奖，授予在帕金森研究方面取得成功的供应商

警示用语：

Danger

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Flam. Sol. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

4.1B - Flammable solid hazardous materials

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SDBB1446
STBL3498
SDBB0489
STBL1038
STBL0660

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The effects of simvastatin on hippocampal caspase-3 and Bcl-2 expression following kainate-induced seizures in rats
Sun J, et al.
International Journal of Molecular Medicine, 30(4), 739-746 (2012)
Cytometry, 256-256 (2000)
Periodate-lysine-paraformaldehyde fixative. A new fixation for immunoelectron microscopy.
I W McLean et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 22(12), 1077-1083 (1974-12-01)
L L Lanier et al.
Journal of immunological methods, 47(1), 25-30 (1981-01-01)
The objective of this study was to find a simple method to preserve cells for subsequent flow cytometry (FACS) analysis. We determined that fixation in 1% paraformaldehyde-0.85% saline solution did not significantly alter the Coulter volume, light scatter of fluorescence
Flow acetone-staining technique: A highly efficient procedure for the simultaneous analysis of DNA content, cell morphology, and immunophenotype by flow cytometry
Carbonari M, et al.
Cytometry. Part A : the Journal of the International Society For Analytical Cytology, 73(2), 168-174 (2008)
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实验方案

蛋白相互作用

本协议描述了一种使用甲醛完成化学交联蛋白质的方法。除零长交联剂外，甲醛是交联跨度最短（~2-3 Å）的交联剂，因此使其成为非常可靠地检测特定蛋白质-蛋白质相互作用的理想工具。

Protein Interactions

Formaldehyde cross-linking protocol detects specific protein interactions with confidence.

Protein Interactions

Formaldehyde cross-linking protocol detects specific protein interactions with confidence.

Protein Interactions

Formaldehyde cross-linking protocol detects specific protein interactions with confidence.

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Questions

1–8 of 8 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. CAN USE TO FIX ZEBRAFISH TISSUE SAMPLES?

    1 answer

    1. Formalin solution (prepared using Paraformaldehyde) has been used to fix adult zebrafish tissue for histological applications.
      Citation: Comparative analysis of fixation and embedding techniques for optimized histological preparation of zebrafish by J.E. Cooper et al., Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 208, 38-46 (2018).
      https://www.sciencedirect.com/science/article/pii/S1532045617302089
      .
      There are likely many other citations in the literature for this application for Paraformaldehyde; the above article is a review article that compares several fixative solutions.

      Helpful?

  4. What is the difference between formaldehyde and paraformaldehyde?

    1 answer

    1. Paraformaldehyde is the polymeric form of formaldehyde. It is a solid. Formaldehyde is a gas which when dissolved in water gives a formaldehyde solution. Commercially available formaldehyde solutions usually contain 10-15% methanol, which prevents the formaldehyde from forming the polymeric paraformaldehyde.

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  5. Do you have a recommended method for preparing solutions of Paraformaldehyde, Product 158127?

    1 answer

    1. Paraformaldehyde does not dissolve but rather can be depolymerized in solution. Depolymerized solutions can be prepared in water with heating to 55-60°C. If necessary, further addition of 1-2 drops of a sodium hydroxide solution may be required. Some protocols suggest that paraformaldehyde should be prepared in buffered solutions such as phosphate buffer or PBS at approximately pH 7.

      Helpful?

  6. How does Product 158127, Paraformaldehyde, compare to prilled paraformaldehyde?

    1 answer

    1. Prilled has the appearance of small white beads.  Product 158127 is a powder, not prilled.

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  7. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  8. How stable are solutions of Product 158127, Paraformaldehyde?

    1 answer

    1. Buffered solutions of 2-4% formaldehyde may be used for up to two weeks if stored in brown bottles at 2-8°C.

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