15785

(−)-薄荷醇

puriss., meets analytical specification of Ph. Eur., BP, USP, 98.0-102.0%

• 别名: (1R,2S,5R)-2-异丙基-5-甲基环己醇, 5-甲基-2-(1-甲基乙基)环己醇
• 经验公式（希尔记法）: C₁₀H₂₀O
• CAS号: 2216-51-5
• 分子量: 156.27
• Beilstein: 1902293
• EC 号: 218-690-9
• MDL编号: MFCD00062979
• UNSPSC代码: 12352001
• PubChem化学物质编号: 57647522
• NACRES: NA.22

属性

• 等级: puriss.
• 质量水平: 200
• 方案: 98.0-102.0%
• 表单: solid
• 旋光性: [α]20/D −48 to −51°, c = 10% in ethanol
• 质量: meets analytical specification of Ph. Eur., BP, USP
• 杂质: acidity or alcalinity, complies; related subst., complies; ≤0.05% non-volatile matter
• mp: 41-44 °C
• 适用性: in accordance for appearance of solution
• 应用: pharmaceutical (small molecule)
• SMILES字符串: CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O
• InChI: 1S/C10H20O/c1-7(2)9-5-4-8(3)6-10(9)11/h7-11H,4-6H2,1-3H3/t8-,9+,10-/m1/s1
• InChI key: NOOLISFMXDJSKH-KXUCPTDWSA-N

说明

一般描述

(-)-Menthol is a monoterpene.[1]

应用

(-)-Menthol may be used to synthesize:

• chiral enantiopure 2-(1-hydroxyalkyl)pyridines, which can react with phosphorus oxychloride to form C3-symmetric tripodal ligands[2]
• menthylphosphorodichioridite, a chiral derivatizing agent for the determination of enantiomeric purity of chiral diols or diamines by ³¹P NMR spectroscopy[3]
• (2R,4S)-2,3,4,5-tetrahydro-2-(-)-menthyloxy-2-methyl-4-phenylpyrano-[3,2-c]-benzopyran-5-one, an intermediate to prepare a warfarin analog[4]

It may also be used as a chiral auxiliary, to induce chirality while synthesizing (-)-horsfiline.[5]

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H315,H319
• 预防措施声明: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• 危险分类: Eye Irrit. 2 - Skin Irrit. 2
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(°F): 201.2 °F - closed cup
• 闪点(°C): 94 °C - closed cup
• 个人防护装备: dust mask type N95 (US), Eyeshields, Gloves