FCMAB418PE-I
Milli-Mark® Anti-CAR-PE Antibody, clone RmcB
clone RmcB, Milli-Mark®, from mouse
别名:
46 kD coxsackievirus and adenovirus receptor (CAR) protein, CVB3 binding protein, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, coxsackie virus B receptor, coxsackie virus and adenovirus receptor
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所有图片(1)
About This Item
分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
推荐产品
生物源
mouse
品質等級
共軛
PE
抗體表格
purified immunoglobulin
抗體產品種類
primary antibodies
無性繁殖
RmcB, monoclonal
物種活性
human
製造商／商標名
Milli-Mark®
技術
flow cytometry: suitable
同型
IgG1
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
目標翻譯後修改
unmodified
基因資訊
human ... CXADR(1525)
一般說明
The coxsackievirus and adenovirus receptor (CAR) mediates cell attachment and infection by coxsackie B viruses and by a number of adenoviruses. CAR also mediates homotypic intercellular interactions. In polarized epithelial cells, CAR is closely associated with the tight junction, where it contributes to the barrier to paracellular flow of solutes and macromolecules. CAR′s biological roles are not well defined, but emerging evidence suggests that it may function during embryonic development and in regulating cell proliferation.
特異性
Antibody recognizes CAR.
免疫原
Native human coxsackie virus-adenovirus receptor protein
應用
Detect CAR using this Milli-Mark Anti-CAR-PE Antibody, clone RmcB validated for use in FC.
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
ECM Proteins
品質
Evaluated by flow cytometry using HT-29 cells.
標靶描述
40 kDa Calculated. Uniprot indicates multiple isoforms ranging from 9 to 40 kDa
外觀
Protein G Purified
Purified mouse monoclonal IgG1 conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.
儲存和穩定性
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
分析報告
Control
HT-29 cells
HT-29 cells
其他說明
Unconjugated version Cat. No. 05-644 is known to react with Mouse and Rat.
法律資訊
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
12 - Non Combustible Liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Michael Klichinsky et al.
Nature biotechnology, 38(8), 947-953 (2020-05-04)
Chimeric antigen receptor (CAR) T cell therapy has shown promise in hematologic malignancies, but its application to solid tumors has been challenging1-4. Given the unique effector functions of macrophages and their capacity to penetrate tumors5, we genetically engineered human macrophages
Hongkang Xi et al.
The Journal of experimental medicine, 213(2), 189-207 (2016-01-13)
Age-related macular degeneration (AMD), a leading cause of vision impairment in the ageing population, is characterized by irreversible loss of retinal pigment epithelial (RPE) cells and photoreceptors and can be associated with choroidal neovascularization. Mononuclear phagocytes are often present in
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