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Merck
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Key Documents

ABN899

Sigma-Aldrich

抗-寡糖-2 抗体

from rabbit, purified by affinity chromatography

别名:

Oligodendrocyte transcription factor 2, bHLHe19, Olg-2, Oligo2, RACK17, RK17

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

mouse, rat, human

技術

immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... OLIG2(10215)

一般說明

少突胶质细胞转录因子2(UniProt Q9EQW6;也称为bHLHe19,Olg-2,Oligo2,RACK17,RK17)由鼠物种中的Olig2(也称为Bhlhb1)基因(基因ID 50913)编码。Olig2是在脊髓心室区域表达的碱性螺旋-环-螺旋(bHLH)转录因子,在胚胎发生过程中介导运动神经元和少突胶质细胞的顺序生成。Olig2在早期时间点还充当pMN祖细胞中的抗神经源性因子,以维持循环祖细胞池。Olig2的抗神经源性也在肿瘤发生中起作用,特别是在脑肿瘤和白血病中。由于其在胶质母细胞瘤和其他弥漫性神经胶质瘤中的表达,Olig2是这些脑肿瘤的有用诊断标志物。

免疫原

KLH偶联线性肽,对应于小鼠Olig-2的N末端区域中的序列。

應用

免疫沉淀分析:10 µg代表性批次免疫沉淀500 µg小鼠脑组织裂解物中的Olig-2。
免疫组化分析:代表性批次的1:500稀释液在大鼠后脑组织切片中检测到Olig-2。
免疫细胞化学分析:代表性批次的1:500稀释液在PC12细胞中检测到Olig-2。
抗Olig-2抗体是针对Olig-2的抗体,用于蛋白质印迹,免疫沉淀,免疫细胞化学,免疫组化(石蜡)。

品質

通过蛋白质印迹在小鼠脑组织裂解液中进行了评估。

蛋白质印迹分析:1.0 µg/mL的该抗体可在10 µg小鼠脑组织裂解物中检测到Olig-2。

標靶描述

观察值〜37 kDa。计算值为32.40 kDa。

聯結

替代品:AB15328

外觀

PBS和0.1 %叠氮化钠中的纯化的兔多克隆抗体。

其他說明

浓度:请参考特定批次的数据表。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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