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Key Documents

AB1570

Sigma-Aldrich

抗GABA转运蛋白-1抗体,CT(a.a.588-599)

Chemicon®, from rabbit

别名:

GAT-1

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

monkey, feline, rat, human, mouse, rabbit

製造商/商標名

Chemicon®

技術

immunohistochemistry: suitable

適合性

not suitable for Western blot

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... SLC6A1(6529)

特異性

GABA转运蛋白-1(GAT-1),C末端。没有检测到与其他发射转运蛋白的C末端的交叉反应性。

免疫原

大鼠GAT-1,C-末端(aa 588-599)
表位:C-端(a.a.588-599)

應用

免疫组化:1:500-1:750,在4%多聚甲醛固定或4%多聚甲醛和0.2%戊二醛固定的组织上。建议用含10%正常山羊血清和0.5%Triton X-100的PBS稀释抗体。AB1570已用于大鼠视网膜、皮层和海马的光学和电子显微镜研究。

注意:不建议将AB1570用于蛋白质印迹。参见AB1570W。

最佳工作稀释度必须由最终用户进行确定。
抗GABA转运蛋白-1抗体,C末端(a.a.588-599)是针对GABA转运蛋白-1的抗体,可用于IH。

外觀

亲和纯化抗体。 从含1%BSA和0.1%叠氮化钠的0.1 M PBS中冻干。用100 μL无菌蒸馏水复溶。

其他說明

浓度:请参考批次特异性浓缩物的检验报告。

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


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Constantino Sotelo
The Journal of comparative neurology, 506(2), 240-262 (2007-11-21)
The acquisition of the dynamic balance between excitation and inhibition in developing Purkinje cells, necessary for their proper function, is analyzed. Newborn (P0) mouse cerebellum contains glutamatergic (VGLUT2-IR) and gamma-aminobutyric acid (GABA)-ergic (VIAAT-IR) axons. The former prevail and belong to
Pericellular innervation of neurons expressing abnormally hyperphosphorylated tau in the hippocampal formation of Alzheimer's disease patients.
Blazquez-Llorca, L; Garcia-Marin, V; Defelipe, J
Frontiers in Neuroanatomy null
Muhamed N H Eeza et al.
Journal of Alzheimer's disease : JAD, 81(2), 797-808 (2021-04-13)
Circadian rhythm disturbance is commonly observed in Alzheimer's disease (AD). In mammals, these rhythms are orchestrated by the superchiasmatic nucleus (SCN). Our previous study in the Tg2576 AD mouse model suggests that inflammatory responses, most likely manifested by low GABA
Lu Pu et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 818451-818451 (2013-02-01)
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation. Here we investigated regulation of GABA transporter GAT1 by δOR in rats and in
Xinjun Wang et al.
The Journal of physiology, 592(19), 4257-4276 (2014-08-03)
GABAergic terminals of chandelier cells exclusively innervate the axon initial segment (AIS) of excitatory neurons. Although the anatomy of these synapses has been well-studied in several brain areas, relatively little is known about their physiological properties. Using vesicular γ-aminobutyric acid

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