8.52016

Fmoc-Phe-OH

Novabiochem^®

• 别名: Fmoc-Phe-OH, N-α-Fmoc-L-phenylalanine
• 经验公式（希尔记法）: C₂₄H₂₁NO₄
• CAS号: 35661-40-6
• 分子量: 387.43
• MDL编号: MFCD00037128
• UNSPSC代码: 12352209
• EC索引号: 252-661-1
• NACRES: NA.22

属性

• 质量水平: 400
• 产品线: Novabiochem^®
• 方案: ≥98% (TLC); ≥98.0% (acidimetric); ≥99.0% (HPLC)
• 表单: powder
• 反应适用性: reaction type: Fmoc solid-phase peptide synthesis
• 制造商/商品名称: Novabiochem^®
• mp: 180-188 °C
• 应用: peptide synthesis
• 官能团: Fmoc
• 储存温度: 2-30°C
• SMILES字符串: N(C(Cc4ccccc4)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
• InChI: 1S/C24H21NO4/c26-23(27)22(14-16-8-2-1-3-9-16)25-24(28)29-15-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h1-13,21-22H,14-15H2,(H,25,28)(H,26,27)
• InChI key: SJVFAHZPLIXNDH-UHFFFAOYSA-N

说明

一般描述

High purity Fmoc-protected amino acid for research and process production of peptides, with very low levels of dipeptide, free-amino acids and acetic acid impurities.
Standard building block for introduction of phenylalanine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Fmoc-amino acids for Peptide Production
Cleavage and Deprotection Protocols for Fmoc SPPS

应用

• Drug release from hydrogels: Utilization in the preparation and optimization of amino acid-based double network hydrogels for photocontrolled drug release, showing promise in drug delivery systems (S Xiang et al., 2024).
• Self-assembling biomaterials: Research on self-assembling Fmoc-Phe-OH peptides for the formation of functional biomaterials, applicable in tissue engineering and regenerative medicine (H Ren et al., 2021).

联系

Replaces: 04-12-1030

分析说明

Colour (visual): white to off white
Appearance of substance (visual): powder
Colour index (0,5 M in DMF): ≤ 150 Hazen
Identity (IR): passes test
Enantiomeric purity: ≥ 99.8 % (a/a)
Purity (HPLC): ≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-ß-Ala-Phe-OH (HPLC): ≤ 0.1 % (a/a)
Fmoc-Phe-Phe-OH (HPLC): ≤ 0.1 % (a/a)
Assay free amino acid (GC): ≤ 0.2 %
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (25 mmole in 50 ml DMF): clearly soluble
Assay (acidimetric): ≥ 98.0 %
Water (K. F.): ≤ 2.0 %
Ethyl acetate (HS-GC): ≤ 0.5 %
Acetate (IC): ≤ 0.02 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable