所有图片(1)
About This Item
经验公式(希尔记法):
C23H25NO6
CAS号:
分子量:
411.45
Beilstein:
3635671
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.26
推荐产品
产品名称
Fmoc-L-天冬氨酸4-叔丁酯, ≥98.0% (HPLC)
方案
≥98.0% (HPLC)
表单
powder
旋光性
[α]20/D −24±2°, c = 1% in DMF
反应适用性
reaction type: Fmoc solid-phase peptide synthesis
mp
148-150 °C (dec.)
应用
peptide synthesis
官能团
Fmoc
储存温度
2-8°C
SMILES字符串
CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
InChI
1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1
InChI key
FODJWPHPWBKDON-IBGZPJMESA-N
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一般描述
Fmoc-Asp(OtBu)-OH又称为Fmoc-L-天冬氨酸4-叔丁酯,在固相多肽合成中用作Fmoc-氨基酸类保护基团。
应用
Fmoc-Asp(OtBu)-OH可用于在Fmoc肽固相合成中防止天冬氨酰亚胺副产物的形成。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
其他客户在看
New t-butyl based aspartate protecting groups preventing aspartimide formation in Fmoc SPPS
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Journal of Peptide Science, 21, 680-687 (2015)
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ACS applied materials & interfaces, 8(44), 29906-29914 (2016-10-21)
In this work, we reported the generation of a novel supramolecular hydrogelator from a peptide derivative which consisted of a structural motif (e.g., Fc-FF) for supramolecular self-assembly and a functional moiety (e.g., RGD) for integrin binding. Following self-assembly in water
Jisi Zhao et al.
Molecules (Basel, Switzerland), 24(4) (2019-03-03)
Photodynamic therapy (PDT) is an established therapeutic modality for the management of cancers. Conjugation with tumor-specific small molecule ligands (e.g., short peptides or peptidomimetics) could increase the tumor targeting of PDT agents, which is very important for improving the outcome
R Ashton Lavoie et al.
Biotechnology and bioengineering, 117(2), 438-452 (2019-10-28)
The clearance of host cell proteins (HCPs) is of crucial importance in biomanufacturing, given their diversity in composition, structure, abundance, and occasional structural homology with the product. The current approach to HCP clearance in the manufacturing of monoclonal antibodies (mAbs)
Stefan Eissler et al.
Journal of peptide science : an official publication of the European Peptide Society, 23(10), 757-762 (2017-06-22)
In solid-phase peptide synthesis, the nominal batch size is calculated using the starting resin substitution and the mass of the starting resin. The starting resin substitution constitutes the basis for the calculation of a whole set of important process parameters
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